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1.
China Journal of Chinese Materia Medica ; (24): 3233-3237, 2020.
Article Dans Chinois | WPRIM | ID: wpr-828453

Résumé

This paper introduces the application and financing of programs of efficacy material base of traditional Chinese medicine funded by the National Natural Science Foundation of China(NSFC), the Youth Science Fund and the Regional Science Fund from 2016 to 2019, and conducts analysis and summary in terms of research objects and analysis methods, with the aim to provide reference for applicants for programs of efficacy material base of traditional Chinese medicine.


Sujets)
Chine , Gestion financière , Fondations , Médecine traditionnelle chinoise , Disciplines des sciences naturelles
2.
Acta Pharmaceutica Sinica ; (12): 813-820, 2010.
Article Dans Chinois | WPRIM | ID: wpr-354570

Résumé

Heat shock protein 90 is a new target of antitumor drug, the inhibitor of Hsp90 fight against tumor by destroy and degrade the structure of protein. In recent years, looking for Hsp90 inhibitor is not only via structure modifying of natural products, but also via high throughput screening and computer aided drug design to find and synthesize new kinds of Hsp90 inhibitor. Anyway, Hsp90 inhibitor has considered as an important biology target and to pay more and more attention. This review describes recent developments of small molecule Hsp90 inhibitors.


Sujets)
Animaux , Humains , Adénine , Chimie , Pharmacologie , Anisoles , Chimie , Pharmacologie , Antinéoplasiques , Chimie , Pharmacologie , Utilisations thérapeutiques , Benzoquinones , Chimie , Utilisations thérapeutiques , Catéchine , Chimie , Pharmacologie , Lignée cellulaire tumorale , Cristallisation , Protéines du choc thermique HSP90 , Chimie , Composés hétérobicycliques , Chimie , Pharmacologie , Lactames macrocycliques , Chimie , Utilisations thérapeutiques , Macrolides , Chimie , Pharmacologie , Structure moléculaire , Tumeurs , Traitement médicamenteux , Anatomopathologie , Pyrazoles , Chimie , Pharmacologie , Relation structure-activité
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