Research advances on the virulence factors of Corynebacterium pseudotuberculosis / 中国人兽共患病学报

Zoonotic pathogen Corynebacterium pseudotuberculosis is the etiological agent of Caseous lymphadenitis (CLA),a chronic infectious disease throughout almost the whole world,which is extremely difficult to control.The pathogenesis of C.pseudotuberculosis is closely related to its virulence factors.In this paper,the virulence factors of C.pseudotuberculosis are reviewed,and it is proposed to further identify and analyze the roles and correlations of other different virulence factors in the pathogenesis of C.pseudotuberculosis infection,which is important for understanding the pathogenic mechanism and identify candidate vaccine of C.pseudotuberculosis.