Résumé
Background: Asymptomatic bacteriuria [ASB] is a risk factor for pyelonephritis and renal dysfunction in diabetic patients
Objective: To investigate the prevalence of and risk factors for ASB among type 2 diabetic female patients
Setting: Chronic Diseases Clinic, Abha Polyclinic, Abha, Saudi Arabia. Design: A Prospective Controlled Study
Method: Two hundred forty-six type 2 diabetic females attending the Chronic Diseases Clinic screened for ASB. Personal characteristics, duration and glycosylated hemoglobin [HbAlc] level were recorded. Four hundred ninety-two age-matched, non-diabetic and apparently healthy females registered at the same polyclinic were used as controls. All participants were followed-up every three months for one year for the development of symptomatic UTI
Result: The mean age of type 2 diabetic females was 50.3 +/- 16.2 years, and 50.4 +/- 15.1 years for non-diabetic [P-Value=0.976]. ASB was detected in 31 [12.6%] diabetic patients and in 32 [6.5%] controls [P-Value=0.005]. E. coli was the most common organism in diabetic patients [18/31, 58.1%] and control subjects [23/32, 71.9%]. Risk factors for ASB among type 2 diabetic females were older age, marriage, duration of diabetes and elevated HbAlc. During the follow-up period, symptomatic UTI developed in 25/31 [80.6%] diabetic patients compared to 39/215 [18.1%] without ASB [P-Value<0.001]
Conclusion: Type 2 diabetic females are at a high risk of developing ASB. Risk factors for ASB include older age, marriage, longer duration of diabetes and high HbAlc