Résumé
Isolated systolic hypertension is common in elderly people and accounts for more than 50% of all cases with hypertension above the age of 65 years. Microalbuminuria represents an early marker of cardiac structural damage
The aim of this work: is to study the relationship between micro albuminuria and subclinical cardiac structural changes [septal wall thickness [SWT], left ventricular mass [LVM] and left ventricular mass index [LVMI]] in isolated systolic hypertension in elderly patients
Result: showed significant positive correlation between microalbuminuria and cardiac structural changes [LVMI - P = 0.001, SWT - P = 0.002 and LVM - P = 0.00011]. There was a significant positive correlation between the duration of hypertension and microalbuminuria, LVM [P=0.02] and LVH [P=0.001]. Also, there was a significant positive correlation between age of patients and LVM [P = 0.01] and LVH [P = 0.01]
Conclusion: taken together this study showed that microalbuminuria represents an early marker of crdiac structural changes in isolated systolic hypertension in elderly patients. It is considered one of the new associated risk factors of hypertension. Cardiovascular prognosis depends not only on the blood pressure level but also on hte presence of target organ damage. So we recommend early detection of microalbuminuria in every hypertensive patient as it is an early sign of endothelial dysfunction and damaged blood vessels
Résumé
Thirty seven eases of needle localisation biopsy were performed in our departments revealing the advantages of this technique. The accuracy of localisation has been checked. There were nine malignant lesions and the rest were benign [75%]. All the malignant eases were discovered at a very early stage and this has been proved by other studies to have a definite positive effect on survival and cure rate