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1.
Tunisie Medicale [La]. 2000; 78 (8-9): 512-517
Dans Français | IMEMR | ID: emr-56005

Résumé

Detection of anti-CMV antibodies was carried out in sera of healthy blood donors, divided into groups of 20 according to age and sex. Sera were tested for anti-CMV by an ELISA test [Enzygnost anti-CMV/IgG-Behring]. Among 280 sera, 272 were positive for IgG to CMV [97.14 percent]. The prevalence of those antibodies was high in all age stratum [95-110 percent] but was higher in women than in men [98.57 percent versus 95.71 percent]. The titre of IgG to CMV was superior to 12 IL/mL in 56.43 percent of CMV positive donors. So, the leucocyle removal is the only alternative for the prevention of post-transfusional CMV infection. The high percentage of donors with anti-CMV antibodies level more than to 12 UL/mL allow to consider the use of plasmapheresis for preparing specific immunoglobulins to CMV


Sujets)
Humains , Mâle , Femelle , Donneurs de sang , Cytomegalovirus/immunologie , Infections à cytomégalovirus , Prévalence , Virus torque teno , Anticorps antiviraux/isolement et purification
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