Rifampicin-Induced Severe Hyperkalemia Requiring Hemodialysis in a Patient with Addison's Disease / 대한신장학회지

Rifampicin, a potent inducer of hepatic microsomal enzymes, increases metabolism of steroid hormone. Therefore, concurrent treatment of rifampicin and steroid may lead to decreased bioavailability and increased requirement of steroid hormone. Here we report a case of rifampicin-induced severe hyperkalemia requiring hemodialysis in a patient with Addison's disease. A 52-year-old woman was admitted due to general weakness. She had been diagnosed with adrenal tuberculosis and consequent Addison's disease and treated with rifampicin and physiologic dose of steroid. Blood chemistry showed 9.1 mEq/L of potassium and emergent hemodialysis was performed. With increment of dosage of steroid hormone and maintenance of the same dosage of rifampicin, potassium level was normalized

Successful Angioplasty of Arteriovenous Graft Obstruction Using Gadolinium chelate in a Patient with Iodine Hypersensitivity / 대한신장학회지

Percutaneous transluminal angioplasty (PTA) using iodine contrast dye has been used as the definitive method of choice for treating hemodialysis vascular access dysfunction. Occasionally, iodine material can not be used in the hemodialysis patients with a history of severe hypersensitivity reactions or the predialysis patients with premature access awaiting hemodialysis treatment. Gadolinium chelates have been reported as an alternative contrast agent for angiography or angioplasty in such patients. Here we report a case of successful angioplasty of arteriovenous graft obstruction using gadolinium chelate (gadopentetate dimeglumine) in a patient with repetitive iodine hypersensitivity reactions.