Résumé
Se presenta el caso de una paciente de 35 años con antecedentes de enfermedad de Basedow-Graves, en tratamiento con propiltiouracilo (PTU), consumidora de pasta base y cocaína, que ingresa por fenómenos trombóticos en extremidades. Presenta en forma brusca falla respiratoria severa, que requiere manejo en UCI. Al laboratorio inmunológico destacan: ANA (+), AntiDNA (+), Anti-Ro (+), Anti-cardiolipinas IgG (+). Se realiza una revisión de las entidades autoinmunes más frecuentes asociadas al uso de drogas.
It presents the case of a 35-year old patient with a history of Basedow Graves disease, under treatment with Propiltiouracile (PTU), crack and cocaine user, who was admitted on thrombotic phenomena in her limbs. She presents sudden severe respiratory failure that requires handling at ICU. Under immunologic lab tests, the following stand out: ANA (+), Anti-DNA (+), Anti-Ro (+), Anti-cardiolipines IgG (+). A checkup is made of the most frequent auto-immune entities associated to drug abuse.
Sujets)
Humains , Adulte , Femelle , Antithyroïdiens , Maladies auto-immunes/induit chimiquement , Propylthiouracile/effets indésirables , Auto-immunité , Lupus érythémateux disséminé/induit chimiquement , Vascularite/induit chimiquementRésumé
Brown tumors are an uncommon manifestation of primary and secondary hyperparathyroidism. We report a 38 years old male consulting for generalized bone pain and prostration caused by multiple osteolytic lesions. Diagnostic work up disclosed a primary hyperparathyroidism secondary to a right parathyroid adenoma. The patient was subjected to a parathyroidectomy. After one year of follow up, symptoms have decreased considerably, laboratory parameters are normal and bone lesions are disappearing.