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Article | IMSEAR | ID: sea-203258

Résumé

Back Ground: Diabetes is not only predisposing factor forcardiovascular disease but once diabetes patients developcoronary artery disease, they have significant worse outcomescompared to other non-diabetic patients.Methods: We studied 80 patients who were admitted for acutecoronary syndrome (ACS), they were classified according tohistory of diabetes mellitus (DM) into 2 groups, Non diabeticgroup 40 patients and Diabetic group 40 patients and then thetwo groups were classified further into sub groups according toelevated markers indicating myocardial injury. Then werefollowed up for 3 months as regard morbidity and mortality.Results: Diabetic patients had significantly higher frequenciesof previous myocardial infarctions, left ventricle (LV)dysfunction, in hospital complications, and rehospitalisation foracute coronary syndrome (ACS) up to death, in comparison tonon-Diabetic patients.Conclusion: From this study, it can be concluded thatelevated biomarkers of myocardial necrosis have adverseeffects on patients either diabetic or non-diabetic on shortterm follow up. Diabetic patients with acute coronary syndrome(ACS) without elevated biomarkers have a mortality andmorbidity risk similar to patients who are not diabetic but haveelevated biomarkers on presentation with acute coronarysyndrome (ACS), and that diabetic patients with elevatedbiomarkers are at highest mortality and morbidity risk.

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