Fabrication and Evaluation of Porous Keratin/chitosan (KCS) Scaffolds for Effectively Accelerating Wound Healing / 生物医学与环境科学（英文）

<p><b>OBJECTIVE</b>To develop a dressing with desired antibacterial activity, good water maintaining ability and mechanical properties for wound healing and skin regeneration.</p><p><b>METHODS</b>The chitosan with different concentrations were added in keratin solution to form porous keratin/chitosan (KCS) scaffolds. The morphological characteristics, chemical composition, wettability, porosity, swelling ratio and degradation of the scaffolds were evaluated. The antibacterial activity was tested by using S. aureus and E. coli suspension for 2 h. And L929 fibroblast cells culture was used to evaluate the cytotoxicity of the KCS scaffolds.</p><p><b>RESULTS</b>The adding of chitosan could increase the hydrophobicity, decrease porosity, swelling ratio and degradation rate of the KCS porous scaffolds. Mechanical properties of KCS scaffolds could be enhanced and well adjusted by chitosan. KCS scaffolds could obviously decrease bacteria number. The proliferation of fibroblast cells in porous KCS patch increased firstly and then decreased with the increase of chitosan concentration. It was appropriate to add 400 μg/mL chitosan to form porous KCS scaffold for achieving best cell attachment and proliferation compared with other samples.</p><p><b>CONCLUSION</b>The porous KCS scaffold may be used as implanted scaffold materials for promoting wound healing and skin regeneration.</p>

Analysis of articles and citations in National Journal of Andrology (2000-2002) / 中华男科学杂志

<p><b>OBJECTIVES</b>To evaluate the academic status and influence of the National Journal of Andrology (NJA).</p><p><b>METHODS</b>The data of articles and citations in 16 issues of NJA (2000-2002) were collected, then the quality of this journal was evaluated in terms of bibliometric parameters.</p><p><b>RESULTS</b>Except for reviews and translations, the sums of original papers accounted for 183 (53.5%), the articles with citation in 16 issues were 333 (97.08%), and funded project papers accounted for 62 (18.08%). The number of the articles and funded project papers increased every year; the average publishing cycle of the articles was 8.7 months; the average number of authors was 3.7 per article; the average age of the first author was 36.3 years old; the authors distributed in 30 provinces, 43.37% of the authors had senior professional title and 40.80% of the authors had master's or doctor's degrees, the journal had a high rate of self-citation (6.30%).</p><p><b>CONCLUSIONS</b>National Journal of Andrology is a high quality journal, with excellent authors, strong influence and bright future.</p>