Musculoskeletal disorders among nurses in high acuity areas in a tertiary hospital in South Africa

The purpose of this cross-sectional study was to investigate the prevalence of musculoskeletal disorders (MSDs) among nurses at a tertiary hospital in South Africa. Self-administered questionnaires were completed by 125 nurses. The mean age of the nurses was 42 years. A high proportion of the nurses reported experiencing musculoskeletal discomfort and related disorders. Most (80.8) worked 12 hour shifts and 84 experienced some form of musculoskeletal discomfort (related to MSDs) in the past year. The lower back was the most commonly reported body site (58); followed by the shoulder (21); and neck (20). Logistic regression analysis showed that nurses working 12 hour shifts had an increased risk of MSD of 14.17 (OR= 14.17; 95 CI: 4.586; 43.766) when compared to those working 8 hours shifts. The number of working hours per shift needs to be reduced to prevent MSDs in nurses. One way of doing this is to increase nursing staff numbers

Prevalence and Profile of Injuries in Khorixas District Hospital; Namibia

The aims of this study were to identify the demographic characteristics of injury victims and the types of injury cases seen and admitted for treatment in Khorixas District Hospital; Namibia. A descriptive retrospective survey of all injuries attended to and admitted in the hospital from January 2001 to December 2004 was done using document review of patients' medical records. A total of 331 injury cases (6.8of all admissions) were admitted. The age group 20-29 years was the most commonly affected; with 18injured. Injury was common among the males (76). The unemployed constituted 36of all the injuries; followed by children/infants (19). Over two-thirds (68) of the injuries were unintentional. Cuts and stabs were the most common (24) type of injury among the injury cases admitted. Motor vehicle accidents accounted for 21of all injuries admitted. Over a third (36) of all the injuries were alcohol related. Farmers (11) constitute the most affected group among the employed. Type of injury and occupation were significantly associated (?2=107.879; p 0.001). Mass propagation of anti-violence education is needed to reduce the high rate of intentional injuries among the injuries such as cuts/stabs; assaults; human bite and gunshot injuries

Perceived Susceptibility of Cervical Cancer Screening among Women Attending Mahalapye District Hospital; Botswana

Cervical cancer is a significant cause of morbidity and mortality in Botswana. Papanicolaou (Pap) cervical cytology screening has helped to reduce cervical cancer rates dramatically through early detection of premalignant lesions in countries with screening programmes that have been well implemented. The objectives of this cross-sectional study were to describe the women's perceived susceptibility to cervical cancer and the association between socio-demographic characteristics. A total of 300 participants were selected by convenience sampling techniques. Participants' mean age was 37 years (SD=11). Results indicated that cervical cancer screening rates were 39. Most of those that had ever been screened for cervical cancer (64); had been screened in the previous three years. Most of the participants (75) were aware of their perceived susceptibility to cervical cancer. There was a significant association between perceived susceptibility and screening for cervical cancer (c2=20.86; p0.001). Among those with low perceived susceptibility to cervical cancer; 31had screened for cervical cancer as compared to 59screening rates among those with high perceived susceptibility to cervical cancer. Those with high perceived susceptibility were 3.2 times more likely to screen for cervical cancer (OR=3.24; 95CI:1.937-5.43) than those with low perceived susceptibility. High susceptibility rates significantly associated with being married (c2=9.44; p=0.051); employed (c2 = 13.077; p 0.001); monthly income more than $411 (c2

Comparative study between clinical and sonographic estimation of fetal weight in third trimester of pregnancy and its relationship with actual birth weight.

This prospective study was undertaken to assess the accuracy of clinical and sonographic estimated fetal weight (EFW) in Bangladeshi population. The study protocol consisted of achieving clinical followed by sonographic estimated fetal weight (uEFW) using Shepard formula and then its correlation with actual birth weight (BW). A total of 140 pregnant women participated in this study. The study was conducted in the department of Radiology & Imaging and in the department of Gynae & Obs., Bangladesh Medical College Hospital (BMCH) from January 2005 to December 2005.Maximum number of patients belonged to 26-30 years age group and the mean +/-SD age of the study patients was 26.8+/-4.7 years. Maximum number of women (41.4%) was primigravida and 24.3% women were second gravida. The mean+/-SD gestational age of the patient was 35.9+/-2.8 weeks. We found, clinically EFW was 3432.1+/-410.1 gm (mean+/-SD) and uEFW was 2715.4+/-509.1gm (mean+/-SD) with difference 716.7+/-278.5 gm (mean+/-SD), (P<0.001), which is highly significant. Babies who were delivered within 1st week of clinical and sonographic EFW were selected and their weights were compared with actual BW. The Pearson correlation chi square test and student 't' test were the statistical analysis used. It was found that the P value of clinical versus actual BW was <0.05, this was significant. P value of sonographic versus actual BW was >0.05, this was not significant. Percent error (PE) was found 2+/-7.33% in calculating uEFW from actual BW with minimum error -23.9% and maximum error 11.81%. This study conducted on Bangladeshi fetus using the Shepard formula showed that the actual BW recorded after delivery of the fetus is more close to uEFW than clinically EFW.

Tumour necrosis factor-alpha as a new therapeutic target for rheumatoid arthritis: an update.

In rheumatoid arthritis (RA), the conventional therapies (first-line, second-line, third-line drugs) provide more or less effective symptomatic relief for a decade or so from the onset of the disease. However, the chronic inflammatory destructive processes involving connective tissue, cartilage and bone with their attendant disability progress relentlessly in majority of patients. Secondly, use of 'second-line' and 'third-line' drugs in RA are limited due to their side effects. Studies in animals and RA patients have confirmed that tumour necrosis factor-alpha (TNFalpha), an inflammatory cytokine, is of major importance in the rheumatoid disease process and thus, it might be an effective therapeutic target in RA. Animal model experiments and clinical trials were conducted with anti-TNFalpha monoclonal antibody (anti-TNFalpha MoAb) in RA recently. This anti-TNFalpha MoAb therapy was found to be both effective and safe which documented the coming-of-age of cytokine-based immunointervention in RA. Researchers are optimistic that modern medicine would certainly witness the application of this noble immunotherapy enabling to selectively target cytokines, e.g. TNFalpha, in RA as well as in other inflammatory autoimmune diseases in the near future.

Analysis of Disability Adjusted Life Years (DALYs) among arsenic victims: a cross-sectional study on health economics perspective.

Arsenic contamination of ground water is a major public health problem in Bangladesh. It is estimated that more than 20 million people are potentially exposed to arsenic poisoning. This cross-sectional study was carried out in Haziganj Upazila under Chandpur district between September to December, 2001 with the objectives to assess the socioeconomic consequences and disease burden in terms of Disability Adjusted Life Years (DALYs). A total of 168 subjects suffering from arsenicosis were studied. Both age and disability weights were considered to calculate DALYs. Agricultural labour and housewives suffered more from the disease. A strong relationship (p<0.005) was found between duration of suffering and occupation of the subjects. Also, there was a strong relationship between age of onset and education of the study subjects (p<0.006). No deaths directly from arsenicosis were reported. It may be noticed that 47% of the patients would be living with disability for more than 51 years. A strong relationship exists (p<0.002) between educational level and Years Lived with Disability (YLDs). A total of 7930 YLDs were lost due to arsenicosis, which accounts for 1908 DALYs.