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1.
Korean Journal of Gastrointestinal Endoscopy ; : 424-427, 2011.
Article Dans Coréen | WPRIM | ID: wpr-150381

Résumé

Neuroendocrine carcinomas mostly occur in the gastrointestinal tract, lung and pancreas. The gallbladder is an uncommon organ for a neuroendocrine carcinoma and it is difficult to diagnose before gallbladder surgery. Owing to its rare occurrence its natural course and treatment are not definitely established. A 71-year-old woman was hospitalized with intermittent abdominal pain and nausea. Abdominal computed tomography showed multiple masses of the gallbladder obstructing the biliary tract. From endoscopic ultrasonography we suspected carcinoma of the gallbladder that was infiltrating a common bile duct. A biopsy was taken using endoscopic retrograde cholangiopancreatography (ERCP) and the mass was diagnosed as a neuroendocrine carcinoma of the gallbladder. Here we report a case of a neuroendocrine carcinoma of the gallbladder confirmed by endoscopic biopsy, and provide a review of the literature.


Sujets)
Sujet âgé , Femelle , Humains , Douleur abdominale , Voies biliaires , Biopsie , Carcinome neuroendocrine , Cholangiopancréatographie rétrograde endoscopique , Conduit cholédoque , Endoscopie , Endosonographie , Vésicule biliaire , Tube digestif , Poumon , Nausée , Pancréas
2.
Korean Journal of Medicine ; : 191-197, 2010.
Article Dans Coréen | WPRIM | ID: wpr-121808

Résumé

BACKGROUND/AIMS: The apolipoprotein B/A-I ratio (ApoB/A-I) is a powerful clinical indicator of atherosclerosis. Although numerous reports have shown the effect of non-alcoholic fatty liver disease (NAFLD) on cardiovascular disease, few reports have examined the relationship between NAFLD and the ApoB/A-I ratio. The aim of the study was to determine the association between NAFLD and the ApoB/A-I ratio in prediabetic patients. METHODS: This cross-sectional study was performed with data obtained from 701 patients (mean age, 47.9+/-9.6 years) diagnosed with prediabetes. Serum lipid profiles including lipoprotein, apolipoprotein, and calculated ApoB/A-I ratio as well as metabolic syndrome parameters such as fasting glucose and insulin were measured in each subject. RESULTS: Among the 701 patients, 340 (48%) had NAFLD. The number of male patients was 490 (NAFLD+, 276; and NAFLD-, 214). The odds ratios for the prevalence of NAFLD increased according to the quartiles of the ApoB/A-I ratio (1.886, 2.245, and 2.587) (p<0.001). CONCLUSIONS: The prevalence of NAFLD correlated with high ApoB/A-I ratio, suggesting that NAFLD increases the risk for atherosclerosis progression in male prediabetic patients.


Sujets)
Humains , Mâle , Apolipoprotéine A-I , Apolipoprotéines , Athérosclérose , Maladies cardiovasculaires , Études transversales , Jeûne , Stéatose hépatique , Glucose , Insuline , Lipoprotéines , Odds ratio , État prédiabétique , Prévalence
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