Résumé
Between November 1992 and June 1995, 309 consecutive patients underwent first-time coronary artery bypass graft [CABG] operation at the Mohammad bin Khalifa bin Sulman Al Khalifa Cardiac Centre. The male female ratio was 5.7: 1, mean age 54.6 years. 41% of patients had urgent or emergency operation, the remainder were elective, 41% were diabetic, 45% hypertensive, 21% hyperlipidaemic, 15% hypercholesterolaemic and 27% had unstable angina, 12% had unstable post-infarction angina within 6 weeks of infarction. Seventeen patients 6% had significant recurrent pulmonary oedema as part of their presentation and 44 [13%] had significant mitral regurgitation. Mean ejection fraction from biplane cineangiography was 41%. A total of 931 distal anastomoses were constructed mean 3.0 grafts per patient. There were 11 hospital deaths [3.56% mortality] and 3 late deaths [1% of hospital survivors] though only 2 late deaths were cardiac. Intra-aortic balloon pumping was used preoperatively in 3 patients [1%] and post-operatively in a further 21 patients [6.7%]. To date, July 1995, no patient has required re-operation though 5 patients have undergone postoperative angioplasty of stenosed internal mammary bypass grafts to the left anterior descending coronary artery in 2 patients and to vessels not significantly diseased or bypassed at the time of operation in 3 patients. All angioplasties were successful in relieving symptoms. The linearised rate of late death, non-fatal myocardial infarction and recurrent angina were 0.8%, and 4.1% per patient year respectively. Actuarial survival free of all cardiac events was 91.2%. Ninety two% of patients out of hospital for three or more months have returned to full-time employment or full activities and only 11 patients are on anti-anginal medical therapy. Despite the diffuse nature of the coronary disease seen in Bahrain and the frequency of previous infarction, reduced ejection fraction, symptomatic pulmonary congestion, diabetes, hypertension and obesity, results with CABG are acceptable in terms of operative mortality and excellent in terms of freedom from 'late' complications and functional rehabilitation
Sujets)
Maladie coronarienne/chirurgie , Infarctus du myocarde/étiologie , Thrombose coronarienne , Hypertension artérielle/anatomopathologieRésumé
Modern invasive cardiology and cardiac surgery is expensive and require intensive resource undertakings. The decision to establish a new cardiac centre, encompassing many specialities must therefore be made with a clear idea of the expected cost and potential benefits expected from such services to deliver to the target population
Sujets)
Chirurgie thoracique , Services de santéRésumé
Over a 16 months period, a total of 200 patients were monitored using the Invos 3100 cerebral oxymeter = which noninvasively measures regional saturation [rSO2] of cerebral microvasculature. From arrival in the operating room rSO2 was recorded along with all normal monitoring parameters in cardiac surgery, viz: patient temperature, blood pressure, central venous pressure, arterial and venous blood gases [VBG]. End-tidalpCO2, inspired oxygen concentration and pump flow. Thirty-four patients [group I], had complete date, 166 patients [group II] did not have VBG done and a subset of 12 group II patients [group III] had rSO2, mean arterial pressure, pump flow and temperature measured every 205 minutes on bypass. No significant correlations could be found between rSO2 and any of these parameters, apart from mean arterial pressure on bypass at nasopharyngeal temperatures below 34°C in group III patients. Monitoring was continued on the intensive care unit until extubation or for the first 24 hours in 183 patients and results were similar. These findings support the contention that monitoring of rSO2 yields unique information, not available with other monitoring systems. Our experience with the routine use of rSO2 monitoring suggests that systems of this type are a valuable adjunct to conventional monitoring. In specific patients,rSO2gave early warning of cerebral circulatory inadequacy due to venous obstruction, was used to monitor the efficacy of cardiopulmonary resuscitation and determine the need for shunting in carotid endarterectomy