Radial Artery Pseudoaneurysm in a Neonate with Hemophilia A.

Background: Pseudoaneurysm formation is a rare complication of arterial puncture. Case characteristics: 3-week-old male developed an enlarging mass over the anterior aspect of left wrist following radial arterial puncture. Observation: Doppler ultrasonography revealed mass to be left radial arterial pseudoaneurysm. Subsequent presentation of ecchymoses and investigations confirmed factor VIII deficiency (Hemophilia A). Outcome: Pseudoaneurysm removed with primary end to end anastomosis. Patient is presently on regular factor VIII replacement therapy. Message: Hemophilia A can present as pseudoaneurysm in neonatal period.

Current Controversies in the Management of Patent Ductus Arteriosus in Preterm Infants.

Objective: Patent ductus arteriosus is very commonly seen in very low birth weight (VLBW) infants, affecting about one-third. The present review tries to identify the group of VLBW infants who need active intervention in day-to-day practice and to determine the mode of intervention, based on current published literatures. Methods: We searched the Cochrane library, MEDLINE, EMBASE and CINAHL databases, and reference that of identified trials. Results and Conclusions: Preterm infants with a birth weight of <800g are at risk of significant morbidity and mortality from PDA; it would be reasonable to treat them when symptomatic or if requiring positive pressure ventilator support. Those weighing >800g are unlikely to need treatment unless they are ventilator-dependent or show evidence of congestive heart failure.