Histopathological and immunohistochemical approach for characterization of undifferentiated malignant tumors

To determine the role of immune-histochemistry in characterization of undifferentiated malignant tumors. Immunohistochemical staining [IHC] performed was Streptavidin-biotin method on paraffin sections, using mono- or polyclonal antibodies and kits manufactured by DAKO corporation [Dako, Denmark A/S]. The technique was applied on 127 cancer cases reported as undifferentiated malignant tumors over a 12 month period, from July 2008 to August 2009. Undifferentiated malignant tumors were more frequently located in the respiratory tract 30 [23.6%], followed by the gastrointestinal tract 25 [19.7%], lymph node 19 [14.9%] and bone/soft tissue 19 [14.9%]. Among these, 75 [82.7%] cases were primary and 22 [17.3%] metastatic. Application of immunohistochemistry resulted in characterization of 112 [88.2%] cases. Non-Hodgkin lymphotma 21 [16.5%] was at the top of the diagnosed list followed by adenocarcinoma 20 [15.7%], sarcoma 17 [13.4%], and small undifferentiated carcinoma 15 [11.8%].Immunohistochemistry is a very helpful tool for characterization of undifferentiated malignant tumors

Histopathological and immunohistochemical approach for characterization of malignant round cell tumors

To analyze the role of immunohistochemistry in characterization of malignant round cell tumors. Immunohistochemical staining [IHC] with [monoclonal or poly-clonal] antibodies was performed on 127 cancer cases reported as malignant round cell tumors over a 12 month period from July 2008 through August 2009. Department of histopathology, Duhok Central Labs. Malignant round cell tumors were more frequently located in the respiratory tract 30 [23.6%] followed by gastrointestinal tract 25 [19.7%], lymph node 19 [14.9%], and bone/soft tissue 19 [14.9%]. Among these, 75[82.7%] cases were primary and 22 [17.3%] metastatic. Application of immunohistochemistry resulted in characterization of 112 [88.2%] cases. Non-Hodgkin lymphoma 21 [16.5%] was at the top of the diagnosed list followed by adenocarcinoma 20 [15.7%], sarcoma 17 [13.4%], and small undifferentiated carcinoma 15 [11.8%].Immunohistochemistry is a very helpful tool for characterization of malignant round cell tumors

Synovial sarcoma of the foot: case report

Synovial sarcoma is a rare soft tissue sarcoma in the foot. It is commonly localized in the extremities, especially the lower thigh and knee areas. The histopathological immunohistochemical, and cytogenetic findings of a foot synovial sarcoma are described