Résumé
Se exponen los datos sobre la antigenicidad de las proteasas de la cucaracha Periplaneta americana y de la vinchuca Triatoma infestans en seres humanos residentes en la CABA y Gran Buenos Aires, así como en las provincias del Norte y Noreste del país. La antigenicidad cruzada entre ambas las convierte en 2 insectos de gran importancia en el ecosistema, y sus restos momificados de estadios adultos y ninfales de trascendencia para diversas patologías infecciosas y respiratorias...
Data concerning the cross-reactivity between the serinproteases of the cockroach Periplaneta Americana and the reduviid Triatoma infestans are exposed. Humans living in Buenos Aires as well as those living in the north of the country inhale mummified particles containing the powerful antigens of both insects and develop chronic respiratory illnesses...
Sujets)
Humains , Blattes/pathogénicité , Maladies de l'appareil respiratoire/étiologie , Triatominae/pathogénicité , Argentine , Maladies transmissibles/étiologieRésumé
Se valoró la posibilidad de que estos mamíferos ingirieron ácaros del hábitat (dermatophagoides pteronyssinus), y que sus antígenos formaran parte de las heces del murciélago (murcielaquina), y resultaren indirectamente alergénicos para los pacientes atópicos que habían revelado hipersensibilidad a dichas heces...
The possibility that house-dust mite antigens coming from dermatophagoides pteronyssinus were hidden in bat feces was studied in those atopic patients suffering rhinitis and asthma that revealed hypersensibility to bat feces...
Sujets)
Humains , Mâle , Femelle , Adulte , Adulte d'âge moyen , Hypersensibilité immédiate/diagnostic , Hypersensibilité immédiate/immunologie , Hypersensibilité respiratoire/diagnostic , Hypersensibilité respiratoire/étiologie , Chiroptera/immunologie , Allergènes , Argentine , Test ELISA , Mites (acariens)/immunologieRésumé
Se aislaron y caracterizaron péptidos del polen de la gramínea Lolium perenne por métodos fisicoquímicos, se estudiaron sus propiedades bioquímicas e inmunológicas, tanto en el conejo como en humanos atópicos que sufrían de rinoconjuntivitis estacional producida por dicho polen, y se presentan los hallazgos inmunoserológicos luego de 3 años de inmunoterapia específica con los péptidos 33 y 38 obtenidos, que resultaron ser los más significativos en la composición fisicoquímica del polen.
Peptides isolated from the Lolium perenne pollen were submitted to several chemical and immunological procedures to establish their antigenicity. Immunotherapy with peptides 33 and 38 showed high potency to develop specific IgG blocking antibodies which correlated with statistical clinical improvement.
Sujets)
Humains , Animaux , Mâle , Femelle , Adulte , Adulte d'âge moyen , Lapins , Antigènes végétaux/immunologie , Antigènes végétaux/usage thérapeutique , Lolium/immunologie , Rhinite allergique saisonnière/diagnostic , Rhinite allergique saisonnière/thérapie , Allergènes , Immunothérapie , Pollen/immunologie , Tests cutanés/méthodes , Tests immunologiques/méthodesRésumé
Data concerning the usefulness of delayed-type hypersensitivity skin tests with recall antigens are exposed. This easy technique has enormous value in the follow-up of the LT dependent immune competence frequently involved in several chronic diseses. We studied 464 patients with ages between 22 and 79 years old. Those 210 healthy controls revealed at least 4,24 ± 1,15 positive skin tests with 1409 ± 287 LTCD4+ cells meanwhile 135 HIV patients showed 2,02 ± 0,80 positive tests with 392 ± 83 LTCD4+ cells and 99 older subjects revealed 2,38 ± 1,15 with 720 ±154 LTCD4+ cells. Statistical differences between the groups were recorded.
Sujets)
Femelle , Groupes témoins , Interprétation statistique de données , Hypersensibilité retardée , Immunité cellulaire/immunologie , Tests cutanésRésumé
Allergic fungal sinusitis is an atopic condition close related to fungus allergens that initiate a chronic inflammation dependent of the IgE system and LTCD4-TH2 cells whose cytokines and chemokines induced the clinical symptoms. Specific immunotherapy is recommended to avoid the recurrences and to improve the benefits of the surgical procedures of the affected sinuses. We suggest that Bipolaris sp Drechslera sp extracts must be included in the skin testing of the atopic patients suffering rhinosinusal symptoms as well as those who reveal intense response to fungal allergens in general.