LARGE PRIMARY RETROPERITONEAL CAVERNOUS HEMANGIOMA

Primary retroperitoneal cavernous hemangioma is a very rare benign neoplasm. A retroperitoneal hemangioma may be detected accidentally or be symptomatic due to local compression on adjacent structures. We reported on the diagnosis and treatment of a patient with PRCH with a subtle clinical presentation and atypical findings on computed tomography imaging. The patient presented with right hypochondriac discomfort for one month duration. Computed tomography of the abdomen revealed a huge mass arising from right lobe of liver which was compressing the surrounding structures. Intraoperatively there was a huge cystic like mass arising from the retroperitoneum which had clear margin with the adjacent structures. The tumour was successfully excised with an intact capsule and histopathological examination revealed a cavernous hemangioma.

Bovine bone xenograft as orbital implants in rabbit eyes / 国际眼科杂志(Guoji Yanke Zazhi)

·AIM: To assess the biocompatibility of bovine bone as orbital implants in rabbits.·METHODS: Bovine bone graft was used as an ocular implant in rabbits to determine whether it could be successfully used in the anophthalmic socket as an alternative to the expensive synthetic alloplastics. Evisceration of eyes with and without bovine bone orbital implantation was performed in the right eyes of 12 New Zealand white rabbits.Group Y (n =6) was eviscerated without implant, meanwhile Group X (n =6) was eviscerated with insertion of an orbital implant using bovine bone. Observation was carried out on day 1, day 7, day 14, day 28 and day 42. Serial clinical examination was carried out based on a few fixed criteria,which included rate of infection, implant migration, evidence of wound breakdown and any restriction of intraocular movements. The implanted eyes were then enucleated on day 42. The enucleated eyes were sent for histopathological evaluation to record the type of inflammatory reaction and rate of fibrovascular ingrowth.·RESULTS: Serial clinical examination showed presence of minimal infection in all eyes, both in Group X implanted) and Group Y (control) on first postoperative day, which responded well with antibiotics. Infection occurred in the implanted group after first postoperative day, but there was no evidence of orbital migration or extrusion of implant, wound breakdown, restriction of extraocular movement, severe infection or any physical abnormality. Histopathological examination revealed good fibrovascular ingrowth in the implanted group, with minimal rejecting reaction of rabbit eye towards bovine bone implant.·CONCLUSION: This study shows that bovine orbital implant has a good biocompatibility in rabbit eyes and its cost is acceptable.