Résumé
Esophageal neuroendocrine carcinomas are very rare and have a poor prognosis. In addition, the optimum treatment has not been established due to the rarity of the condition. An accurate differential diagnosis is important because treatments and clinical courses differ from those of esophageal squamous cell carcinomas. We report a case of a 61-year-old female who underwent endoscopy for dysphagia and was diagnosed with a neuroendocrine carcinoma of the esophagus, which was successfully resected by esophagectomy.
Sujets)
Femelle , Humains , Carcinome neuroendocrine , Carcinome épidermoïde , Troubles de la déglutition , Diagnostic différentiel , Endoscopie , Oesophagectomie , Oesophage , Tumeurs neuroendocrines , PronosticRésumé
Polymyositis is characterized by symmetrical proximal muscle weakness, nonsuppurative inflammation of skeletal muscle, elevation of muscle enzyme levels, and abnormality of electromyographical change. Its pathogenesis is unclear. Paraneoplastic syndromes are caused by malignant tumors, although not through direct effects of the primary tumor or its metastases. Several paraneoplastic syndromes, including erythrocytosis, hypoglycemia, and hypercholesterolemia, have been reported in patients with hepatocellular carcinoma. A few cases of polymyositis associated with hepatocellular carcinoma and one case of combined hepatocellular-cholangiocarcinoma associated with polymyositis and chronic hepatitis B virus infection have been reported. Skeletal muscle injuries without trauma, including metabolic myopathy, effects of certain drugs and toxins, infection, electrolyte imbalances, and endocrine disorders, may cause rhabdomyolysis. We present here a case of primary liver cancer associated with polymyositis and rhabdomyolysis.
Sujets)
Humains , Carcinome hépatocellulaire , Hépatite B chronique , Hypercholestérolémie , Hypoglycémie , Inflammation , Foie , Tumeurs du foie , Faiblesse musculaire , Muscles squelettiques , Muscles , Maladies musculaires , Métastase tumorale , Syndromes paranéoplasiques , Polyglobulie , Polymyosite , Rhabdomyolyse , VirusRésumé
Polymyositis is characterized by symmetrical proximal muscle weakness, nonsuppurative inflammation of skeletal muscle, elevation of muscle enzyme levels, and abnormality of electromyographical change. Its pathogenesis is unclear. Paraneoplastic syndromes are caused by malignant tumors, although not through direct effects of the primary tumor or its metastases. Several paraneoplastic syndromes, including erythrocytosis, hypoglycemia, and hypercholesterolemia, have been reported in patients with hepatocellular carcinoma. A few cases of polymyositis associated with hepatocellular carcinoma and one case of combined hepatocellular-cholangiocarcinoma associated with polymyositis and chronic hepatitis B virus infection have been reported. Skeletal muscle injuries without trauma, including metabolic myopathy, effects of certain drugs and toxins, infection, electrolyte imbalances, and endocrine disorders, may cause rhabdomyolysis. We present here a case of primary liver cancer associated with polymyositis and rhabdomyolysis.
Sujets)
Humains , Carcinome hépatocellulaire , Hépatite B chronique , Hypercholestérolémie , Hypoglycémie , Inflammation , Foie , Tumeurs du foie , Faiblesse musculaire , Muscles squelettiques , Muscles , Maladies musculaires , Métastase tumorale , Syndromes paranéoplasiques , Polyglobulie , Polymyosite , Rhabdomyolyse , VirusRésumé
Cogan's syndrome is a rare systemic inflammatory disease and can be diagnosed on the basis of typical inner ear and ocular involvement with the presence of large vessel vasculitis. We report a case of Cogan's syndrome with stable angina resulting from coronary ostial stenosis caused by aortitis.
Sujets)
Angine de poitrine , Angor stable , Aortite , Syndrome de Cogan , Sténose pathologique , Oreille interne , Glycosaminoglycanes , VasculariteRésumé
Coronary vasospasm plays an important role in the pathogenesis not only of variant angina, but also of ischemic heart disease in general, including other forms of angina pectoris, acute myocardial infarction, and sudden death. Vasoactive events leading to an acute reduction in regional myocardial flow in the presence of a normal or previously compromised circulation are a common cause of arrhythmias. However, coronary vasospasm-induced electrical and mechanical complications are rarely reported in patients with angiographically normal or near-normal coronary arteries. This paper presents our experience with a patient presenting with coronary vasospasm-associated ventricular fibrillation without findings of significant coronary artery disease.
Sujets)
Humains , Angine de poitrine , Angine de poitrine variante , Troubles du rythme cardiaque , Maladie des artères coronaires , Spasme coronaire , Vaisseaux coronaires , Mort subite , Infarctus du myocarde , Ischémie myocardique , Fibrillation ventriculaireRésumé
Coronary vasospasm plays an important role in the pathogenesis not only of variant angina, but also of ischemic heart disease in general, including other forms of angina pectoris, acute myocardial infarction, and sudden death. Vasoactive events leading to an acute reduction in regional myocardial flow in the presence of a normal or previously compromised circulation are a common cause of arrhythmias. However, coronary vasospasm-induced electrical and mechanical complications are rarely reported in patients with angiographically normal or near-normal coronary arteries. This paper presents our experience with a patient presenting with coronary vasospasm-associated ventricular fibrillation without findings of significant coronary artery disease.