Sujets)
Adolescent , Adulte , Analgésie obstétricale , Bromure de N-butyl-scopolammonium/administration et posologie , Méthode en double aveugle , Femelle , Humains , Injections veineuses , Douleur de l'accouchement/diagnostic , Antagonistes muscariniques/administration et posologie , Mesure de la douleur , Grossesse , Jeune adulteRésumé
Insufficient attention is paid to the need for assessing the mental capacity of participants in clinical trials, particularly those in psychiatry. Assessment of mental capacity is paramount especially in patients suffering from certain brain disorders and psychiatric illnesses, as lack of capacity can invalidate the consent given. Suggested below is a framework for assessing mental capacity in a systematic way with the hope that those writing on the subject of clinical research give it due importance.
Sujets)
Essais cliniques comme sujet , Humains , Consentement libre et éclairé , Capacité mentale/classification , Troubles psychotiquesRésumé
People with schizophrenia are at greater risk of developing obesity, type 2 diabetes, hypertension and dyslipidemia as compared to the general population. This results in an increased incidence of cardiovascular disease, leading to greater morbidity and mortality in this vulnerable group of patients. Use of certain antipsychotic agents can compound this risk and increase the risk of developing metabolic syndrome. Appropriate identification and management of these risk factors are very important in reducing the risk and thereby improving the physical health of these patients. This review recommends a framework based on existing guidelines for the assessment, monitoring and management of patients with schizophrenia in the Indian setting.