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1.
Journal of Korean Medical Science ; : e118-2023.
Article Dans Anglais | WPRIM | ID: wpr-976932

Résumé

Background@#Long commuting times have a negative impact on mental health. However, few studies have explored the relationship between commuting time and well-being based on urbanization by region. Our study examines this relationship as well as the effect of regional differences on Korean workers. @*Methods@#We used data from the sixth Korean Working Conditions Survey. Commuting time and occupational factors were assessed using a questionnaire, and subjective well-being was assessed using the World Health Organization-5 Well-Being Index. Regions were divided into the cities and the provinces based on Korea’s administrative divisions. Logistic regression analysis was performed to investigate the association between commuting time and wellbeing. Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) for well-being were estimated, using participants commuting time of < 20 minutes as a reference group. @*Results@#The total number of workers was 29,458 (13,855 men, 15,603 women). We found higher aORs for low well-being among workers with long commuting times (aOR, 1.23; 95% CI, 1.11–1.36 and aOR, 1.28; 95% CI, 1.16–1.42 for 60–79 and ≥ 80 minutes, respectively). When stratified by sex and region, higher aORs for low well-being were found only in the workers who lived in cities. @*Conclusion@#Long commuting time was negatively associated with well-being in Korean wage workers living in the cities. Policies for reducing commuting time should be discussed to address the mental health of workers, especially those living in metropolitan cities.

2.
Annals of Occupational and Environmental Medicine ; : e18-2020.
Article Dans Anglais | WPRIM | ID: wpr-896854

Résumé

Background@#Change in working time arrangement (WTA) can be harmful to workers' sleep and health. This study aimed to investigate the association between change in working time arrangement and sleep disturbance. @*Methods@#This study used data from the Fifth Korean Working Condition Survey and included 33,203 paid workers. We performed a stratified analysis by sex. After dividing the participants into 6 groups based on whether or not they experienced WTA changes, and their weekly working hours (≤40, 41–52, ≥53 hours), we calculated odds ratio (OR) using the weekly working hours ≤40 hours and with no WTA change as the reference group. @*Results@#Of the 33,203 paid workers, participants who experienced change in working time arrangement had higher prevalence of all three types of sleep disturbance symptoms (difficulty in falling asleep, waking up repeatedly during sleep, and waking up with a feeling of exhaustion and fatigue) in both sexes. Compared to the reference group at 95% confidence interval (CI), the group with change in WTA showed elevated OR values of 1.91 (95% CI:1.73–2.11), 1.93 (95% CI: 1.74–2.14), 2.47 (95% CI: 2.26–2.71) for male workers; and 1.93 (95% CI: 1.73–2.16), 2.02 (95% CI: 1.80–2.27), 2.24 (95% CI: 2.01–2.50) for female workers, for difficulty in falling asleep, waking up repeatedly during the sleep, waking up with a feeling of exhaustion, and fatigue, respectively. @*Conclusions@#Workers who experience change in work time arrangement show a high risk of sleep disturbance in both sexes.

3.
Annals of Occupational and Environmental Medicine ; : e18-2020.
Article Dans Anglais | WPRIM | ID: wpr-889150

Résumé

Background@#Change in working time arrangement (WTA) can be harmful to workers' sleep and health. This study aimed to investigate the association between change in working time arrangement and sleep disturbance. @*Methods@#This study used data from the Fifth Korean Working Condition Survey and included 33,203 paid workers. We performed a stratified analysis by sex. After dividing the participants into 6 groups based on whether or not they experienced WTA changes, and their weekly working hours (≤40, 41–52, ≥53 hours), we calculated odds ratio (OR) using the weekly working hours ≤40 hours and with no WTA change as the reference group. @*Results@#Of the 33,203 paid workers, participants who experienced change in working time arrangement had higher prevalence of all three types of sleep disturbance symptoms (difficulty in falling asleep, waking up repeatedly during sleep, and waking up with a feeling of exhaustion and fatigue) in both sexes. Compared to the reference group at 95% confidence interval (CI), the group with change in WTA showed elevated OR values of 1.91 (95% CI:1.73–2.11), 1.93 (95% CI: 1.74–2.14), 2.47 (95% CI: 2.26–2.71) for male workers; and 1.93 (95% CI: 1.73–2.16), 2.02 (95% CI: 1.80–2.27), 2.24 (95% CI: 2.01–2.50) for female workers, for difficulty in falling asleep, waking up repeatedly during the sleep, waking up with a feeling of exhaustion, and fatigue, respectively. @*Conclusions@#Workers who experience change in work time arrangement show a high risk of sleep disturbance in both sexes.

4.
Annals of Occupational and Environmental Medicine ; : e13-2019.
Article Dans Anglais | WPRIM | ID: wpr-762565

Résumé

BACKGROUND: Dependent self-employment is precarious employment, which can be vulnerable to mental health problems. This study aimed to investigate the association of dependent self-employment with depression, anxiety, and sleep disorder in South Korea. METHODS: This study used data from the Fourth Korean Working Conditions Survey and included 32,691 paid workers. Dependent self-employment and self-reported depression/anxiety, and sleep disorder were investigated using a questionnaire. Logistic regression analysis was performed to investigate the association between dependent self-employment and mental health problems. RESULTS: Of the 32,691 paid workers, 2,371 (7.3%) were dependent self-employed workers. The odds ratio (OR) of dependent self-employment for self-reported depression/anxiety was 1.78 (95% confidence interval [CI]: 1.29–2.45) and the OR of dependent self-employment for self-reported sleep disorder was 1.26 (95% CI: 1.01–1.59) compared to other paid workers. CONCLUSIONS: Dependent self-employment is related to an increased risk of self-reported depression/anxiety and sleep disorder in South Korea.


Sujets)
Anxiété , Dépression , Emploi , Corée , Modèles logistiques , Santé mentale , Odds ratio , Troubles de la veille et du sommeil
5.
Annals of Occupational and Environmental Medicine ; : 19-2018.
Article Dans Anglais | WPRIM | ID: wpr-762529

Résumé

BACKGROUND: On-call work is a form of work that requires the person to work at any time during the on-call period. Thus, on-call work is often regarded as one of the most severe stress factors. This study investigates the associations between on-call work and health problems, injuries. METHODS: This study was based on the 3rd Korean Working Conditions Survey. Total of 29,246 employed workers who had been working for at least 1 year were included. Logistic regression analysis was performed to investigate the association between on-call work and health problems, injuries. RESULTS: The odds ratios for on-call workers in terms of physical health problems, psychological health problems, and injuries were 1.33 (95% confidence interval [CI] 1.22-1.44), 1.31 (95% CI 1.08-1.60), and 2.76 (95% CI 2.26-3.37), respectively. Analysis of the detailed symptoms revealed odds ratios in on-call workers of 2.06 for hearing problems (95% CI 1.63-2.62); 1.71 for skin problems (95% CI 1.38-2.12); 1.22 for back pain (95% CI 1.08-1.38); 1.23 for muscular pains in upper limbs (95% CI 1.12-1.34); 1.27 for muscular pains in lower limbs (95% CI 1.15-1.40); 1.46 for headache, eye fatigue (95% CI 1.32-1.60); 1.37 for abdominal pain (95% CI 1.02-1.85); 1.43 for depression or anxiety disorders (95% CI 1.07-1.93); 1.36 for fatigue (95% CI 1.24-1.49); and 1.41 for insomnia and general sleep difficulties (95% CI 1.13-1.76). CONCLUSIONS: The present study found that on-call work results in an increased risk of health problems and injuries. This study is the result of analyses of broad range of the job spectrum in Korean employed workers; thus, future studies are necessary to determine the effects of on-call work in various job groups.


Sujets)
Humains , Douleur abdominale , Troubles anxieux , Asthénopie , Dorsalgie , Dépression , Fatigue , Céphalée , Ouïe , Modèles logistiques , Membre inférieur , Odds ratio , Peau , Troubles de l'endormissement et du maintien du sommeil , Membre supérieur
6.
Annals of Occupational and Environmental Medicine ; : 39-2018.
Article Dans Anglais | WPRIM | ID: wpr-762509

Résumé

BACKGROUND: Prospective studies on occupational stress and depression among Korean workers are scarce. This study aimed to investigate the causal relationship between changes in occupational stress and the presence of depression. METHODS: This study analyzed data from a survey conducted with workers in a large Korean company (2015–2016). Occupational stress was measured using the Korean Occupational Stress Scale, and depression was screened using the WHO-5 Well-being Index. The levels of occupational stress were grouped in quartiles based on subjects’ occupational stress scores in 2015, and changes in occupational stress were measured using the score changes between the 2015 and 2016 surveys. Subjects were divided into four groups according to the presence or absence of depression in 2015 and 2016: a non-depressed group whose mental health did not change, a non-depressed group whose mental health deteriorated, a depressed group that continued to be depressed, and a depressed group whose symptoms of depression were alleviated. Logistic regression analysis was used to calculate the odds ratios (ORs) and confidence intervals (CIs) of the subjects’ deterioration in mood or alleviation of depression by occupational stress levels and changes. RESULTS: The OR for developing depressive symptoms was 2.51 (95% CI 1.46–4.33) and 2.73 (95% CI 1.39–5.36) in the third and the fourth quartiles of occupational stress, respectively, compared to the first quartile. When the occupational stress score increased by 1 point, the OR for increasing depressive symptoms was 1.07 (95% CI 1.04–1.10). There was no significant difference in the alleviation of depressive symptoms between the groups by level of occupational stress. However, when the occupational stress score decreased by 1 point, the OR for alleviating depressive symptoms was 1.08 (95% CI 1.05–1.11). CONCLUSION: The results showed that increased occupational stress increased the presence of depressive symptoms, and that reduced occupational stress suppressed the development of depressive symptoms. More attention should be paid to stress management among workers.


Sujets)
Dépression , Modèles logistiques , Études longitudinales , Santé mentale , Odds ratio , Études prospectives
7.
Journal of Korean Medical Science ; : e2-2018.
Article Dans Anglais | WPRIM | ID: wpr-764852

Résumé

BACKGROUND: Despite the necessity of job retention in achieving return-to-work (RTW) goals, many workers leave their jobs after returning to work. The objective of this study was to examine the impacts of RTW type and period on job retention in Korean workers with occupational injuries and diseases. METHODS: Data were derived from the Panel Study of Worker's Compensation Insurance, including data from 2,000 systemically sampled workers who had finished recuperation in 2012; three waves of survey data were included in the analyses. Workers who returned to work (n = 1,610) were included in the analysis of the relationship between RTW type and job retention, and 664 workers who returned to their original workplaces were included in the analysis of the relationship between RTW period and job retention. The participants completed a questionnaire, and administrative data were provided by workers' compensation insurance. RESULTS: A Cox proportional-hazards regression analysis showed an increased hazard ratio (HR) for non-retention of 2.66 (95% confidence interval, 2.11–3.35) in reemployed workers compared to that in workers returning to their original workplaces. Among workers returning to their original workplaces, HRs for non-retention were increased in workers with a RTW period of 13–24 months (3.03 [1.52–6.04]) and > 24 months (5.33 [2.14–13.25]) compared to workers with a RTW period of ≤ 3 months. CONCLUSION: RTW type and period were significantly related to job retention, suggesting that policies for promoting job retention rate should be implemented.


Sujets)
Assurance , Maladies professionnelles , Santé au travail , Blessures professionnelles , Reprise du travail , Indemnisation des accidentés du travail
8.
Annals of Occupational and Environmental Medicine ; : 43-2016.
Article Dans Anglais | WPRIM | ID: wpr-68566

Résumé

BACKGROUND: This research was conducted with an aim of determining the association between employment status and self-rated health. METHODS: Using the data from the Third Korean Working Conditions Survey conducted in 2011, We included data from 34,783 respondents, excluding employers, self-employed workers, unpaid family workers, others. Self-rated health was compared according to employment status and a logistic regression analysis was performed. RESULTS: Among the 34,783 workers, the number of permanent and non-permanent workers was 27,564 (79.2 %) and 7,219 (20.8 %). The risk that the self-rated health of non-permanent workers was poor was 1.20 times higher when both socio-demographic factors, work environment and work hazards were corrected. CONCLUSIONS: In this study, perceived health was found to be worse in the non-permanent workers than permanent workers. Additional research should investigate whether other factors mediate the relationship between employment status and perceived health.


Sujets)
Humains , Emploi , Modèles logistiques , Enquêtes et questionnaires
9.
Annals of Occupational and Environmental Medicine ; : 41-2016.
Article Dans Anglais | WPRIM | ID: wpr-59534

Résumé

BACKGROUND: Presenteeism, a concept that has recently undergone active study, is the act of attending work while sick. This study investigates the association between presenteeism and various psychosocial factors within workplaces. METHODS: This study analyzed 29246 wage earners from the third Korean Working Conditions Survey (KWCS, 2011) data using the logistic regression analysis to investigate the association between presenteeism and various psychosocial factors within workplaces. RESULTS: Among the 29246 wage earners, 6347 (21.7 %) showed presenteeism. Those who experienced age discrimination at work (adjusted odds ratio (aOR) 1.77: 95 % CI 1.56–2.00), educational background discrimination (aOR 1.35: 95 % CI 1.22–1.51), regional discrimination (aOR 1.55: 95 % CI 1.31–1.83), sexual discrimination (aOR 1.65: 95 % CI 1.41–1.94), employment type discrimination (aOR 2.13: 95 % CI 1.89–2.40), physical violence (aOR 1.92: 95 % CI 1.45–2.55), sexual harassment (aOR 2.90: 95 % CI 2.01–4.19), job insecurity (aOR 1.36: 95 % CI 1.18–1.56), work–life imbalance (aOR 1.38: 95 % CI 1.29–1.47), low job satisfaction (aOR 2.04: 95 % CI 1.91–2.17), no colleague support (aOR 1.11: 95 % CI 1.02–1.21), job stress (aOR 1.89: 95 % CI 1.76–2.02), emotional labor (aOR 1.50: 95 % CI 1.41–1.60), high work intensity (aOR 1.31: 95 % CI 1.23–1.38), and 3 groups of job strain that are passive group (aOR 1.09: 95 % CI 1.00–1.18), active group (aOR 1.39: 95 % CI 1.28–1.51), and high strain group (aOR 1.35: 95 % CI 1.24–1.46) showed an increased risk of presenteeism compared to their respective counterparts (p < 0.01). CONCLUSIONS: The study results confirmed the association between presenteeism and various psychosocial factors within workplaces. Considering that presenteeism negatively affects productivity and the mental and physical health of individuals, managing various psychosocial factors within workplaces is proposed to reduce presenteeism.


Sujets)
Âgisme , , Rendement , Emploi , Satisfaction professionnelle , Modèles logistiques , Odds ratio , Sévices , Présentéisme , Psychologie , Salaires et prestations accessoires , Harcèlement sexuel
10.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 328-334, 2015.
Article Dans Anglais | WPRIM | ID: wpr-128346

Résumé

BACKGROUND: There have been a number of studies on mitral valve replacement and repeated percutaneous mitral balloon valvotomy for mitral valve restenosis after percutaneous mitral balloon valvotomy. However, studies on mitral valve repair for these patients are rare. In this study, we analyzed postoperative outcomes of mitral valve repair for mitral valve restenosis after percutaneous mitral balloon valvotomy. METHODS: In this study, we assessed 15 patients (mean age, 47.7+/-9.7 years; 11 female and 4 male) who underwent mitral valve repair between August 2008 and March 2013 for symptomatic mitral valve restenosis after percutaneous mitral balloon valvotomy. The mean interval between the initial percutaneous mitral balloon valvotomy and the mitral valve repair was 13.5+/-7 years. The mean preoperative Wilkins score was 9.4+/-2.6. RESULTS: The mean mitral valve area obtained using planimetry increased from 1.16+/-0.16 cm2 to 1.62+/-0.34 cm2 (p=0.0001). The mean pressure half time obtained using Doppler ultrasound decreased from 202.4+/-58.6 ms to 152+/-50.2 ms (p=0.0001). The mean pressure gradient obtained using Doppler ultrasound decreased from 9.4+/-4.0 mmHg to 5.8+/-1.5 mmHg (p=0.0021). There were no early or late deaths. Thromboembolic events or infective endocarditis did not occur. Reoperations such as mitral valve repair or mitral valve replacement were not performed during the follow-up period (39+/-16 months). The 5-year event-free survival was 56.16% (95% confidence interval, 47.467-64.866). CONCLUSION: On the basis of these results, we could not conclude that mitral valve repair could be an alternative for patients with mitral valve restenosis after percutaneous balloon mitral valvotomy. However, some patients presented with results similar to those of mitral valve replacement. Further studies including more patients with long-term follow-up are necessary to determine the possibility of this application of mitral valve repair.


Sujets)
Femelle , Humains , Valvuloplastie par ballonnet , Survie sans rechute , Endocardite , Études de suivi , Valve atrioventriculaire gauche , Échographie
11.
Annals of Occupational and Environmental Medicine ; : 11-2015.
Article Dans Anglais | WPRIM | ID: wpr-52303

Résumé

OBJECTIVE: This study investigated the impact of occupation on cognitive and physical function within an occupational window of the past 15 years using a nationally representative sample in Korea. METHODS: A total of 4,408 subjects aged 60 and older were selected from the Korean Longitudinal Study of Aging (KLoSA). Functional health was evaluated using the Korean versions of the Mental State Examination (K-MMSE), Instrumental Activities of Daily Living (K-IADL), and Activities of Daily Living (K-ADL) measures. RESULTS: The prevalence of lower function was higher among women than among men, and employed persons had better cognitive and physical function compared with the retired and unemployed. Longer work duration during the past 15 years significantly and positively affected all measures of function in men, whereas it only improved physical function in women. Manual laborers exhibited improved functional capacity with longer work durations over the past 15 years, although they presented lower functional scores compared with non-manual laborers. There was a curvilinear relationship of work duration with cognitive and physical function among men and manual laborers. CONCLUSION: In our population, longer work duration, especially for men and for manual laborers, appears to be a significant contributor to the cognitive and physical function of older people.


Sujets)
Adulte , Femelle , Humains , Mâle , Activités de la vie quotidienne , Vieillissement , Corée , Études longitudinales , Professions , Prévalence
12.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 249-254, 2014.
Article Dans Anglais | WPRIM | ID: wpr-215832

Résumé

BACKGROUND: Delirium after cardiac surgery is associated with serious long-term negative outcomes and high costs. The aim of this study is to evaluate neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine, compared with the current postoperative sedative protocol (remifentanil) in patients undergoing open heart surgery with cardiopulmonary bypass (CPB). METHODS: One hundred and forty two eligible patients who underwent cardiac surgery on CPB between April 2012 and March 2013 were randomly divided into two groups. Patients received either dexmedetomidine (range, 0.2 to 0.8 microg/kg/hr; n=67) or remifentanil (range, 1,000 to 2,500 microg/hr, n=75). The primary end point was the prevalence of delirium estimated daily via the confusion assessment method for intensive care. RESULTS: When the delirium incidence was compared with the dexmedetomidine group (6 of 67 patients, 8.96%) and the remifentanil group (17 of 75 patients, 22.67%) it was found to be significantly less in the dexmedetomidine group (p<0.05). There were no statistically significant differences between two groups in the extubation time, ICU stay, total hospital stay, and other postoperative complications including hemodynamic side effects. CONCLUSION: This preliminary study suggests that dexmedetomidine as a postoperative sedative agent is associated with significantly lower rates of delirium after cardiac surgery.


Sujets)
Adulte , Humains , Pontage cardiopulmonaire , Délire avec confusion , Dexmédétomidine , Hémodynamique , Incidence , Soins de réanimation , Durée du séjour , Soins postopératoires , Complications postopératoires , Prévalence , Chirurgie thoracique
13.
Journal of Preventive Medicine and Public Health ; : 124-128, 2014.
Article Dans Anglais | WPRIM | ID: wpr-218973

Résumé

OBJECTIVES: To evaluate the monthly variation in the airborne (1-->3)-beta-D-glucan level throughout one year and its relationship with climatic factors (temperature, relative humidity, wind speed, hours of daylight, cloud cover, and pollen counts). METHODS: A total of 106 samples were collected using a two-stage cyclone sampler at five outdoor sampling locations (on top of 5 university buildings). The kinetic limulus amebocyte lysate assay was used to obtain (1-->3)-beta-D-glucan levels. RESULTS: Airborne (1-->3)-beta-D-glucan levels were significantly higher in the spring, particularly in April, and temperature was significantly related to (1-->3)-beta-D-glucan levels (r =0.339, p3)-beta-D-glucan levels may be highest in the spring, and outdoor temperature may influence (1-->3)-beta-D-glucan levels.


Sujets)
Polluants atmosphériques/analyse , Surveillance de l'environnement , Glucanes/analyse , Humidité , Saisons , Température , Vent
14.
Annals of Occupational and Environmental Medicine ; : 32-32, 2014.
Article Dans Anglais | WPRIM | ID: wpr-147026

Résumé

OBJECTIVE: Presenteeism has become a public concern recently. Thus, we aimed to understand the relationship between self-employed workers and presenteeism using a nationally representative sample of Korean workers. METHODS: Using data from the Korean Working Conditions Survey conducted in 2011, a total of 43,392 workers including paid employees and self-employed workers were analyzed. The effect of employment status on presenteeism was analyzed using logistic regression analysis. The independent variables were socioeconomic characteristics, working conditions, and working environments. RESULTS: Among the 43,392 workers, 34,783 were paid and 8,609 were self-employed. Self-employed workers were more likely to exhibit presenteeism than were paid workers. An elevated odds ratio of 1.27 (95% CI 1.19-1.36) was found for presenteeism among self-employed workers. CONCLUSION: Being self-employed was significantly related with exhibiting presenteeism. Additional research should investigate whether other factors mediate the relationship between employment status and presenteeism as well as ways to reduce presenteeism among self-employed workers.


Sujets)
Absentéisme , Emploi , Modèles logistiques , Odds ratio
15.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 145-148, 2014.
Article Dans Anglais | WPRIM | ID: wpr-24187

Résumé

Here, we present a rare case of cardiac parasitic infection found in an adult female patient who had the symptoms of dyspnea upon exertion. She was diagnosed with a double-chambered right ventricle due to infundibular hypertrophy confirmed by transthoracic echocardiography and cardiac computed tomography. We performed surgery of infundibulectomy around the pulmonary valve. In the end, histopathological findings of the resected infundibular muscle demonstrated trichinellosis, a type of roundworm infection.


Sujets)
Adulte , Femelle , Humains , Dyspnée , Échocardiographie , Ventricules cardiaques , Hypertrophie , Valve du tronc pulmonaire , Trichinellose
16.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 167-170, 2014.
Article Dans Anglais | WPRIM | ID: wpr-24181

Résumé

Herein, we present a case of a successful treatment of persistent type 2 endoleaks associated with aneurysmal sac enlargement after endovascular aneurysm repair in an elderly patient. We confirmed the diagnosis by abdominal computed tomography and selective angiography revealing an 11.0-cm aneurysm sac with type 2 endoleaks. An attempt for the endovascular embolization of collateral arteries was unsuccessful due to anatomic variations and their multiple complex communications. Instead, transperitoneal sacotomy and direct suturing on the feeding target vessels was successfully performed without any endograft damage. In conclusion, sacotomy appears to be a feasible therapeutic substitute where endovascular or other techniques have a high risk of failure and lead to unsuccessful results.


Sujets)
Sujet âgé , Humains , Anévrysme , Angiographie , Artères , Diagnostic , Endofuite , Prothèses et implants
17.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 185-191, 2013.
Article Dans Anglais | WPRIM | ID: wpr-129700

Résumé

BACKGROUND: Cardiopulmonary bypass (CPB) induces variable systemic inflammatory reactions associated with major organ dysfunction via polymorphonuclear neutrophils (PMNs). Ulinastatin, a urinary trypsin inhibitor, inhibits PMN activity and reduces systemic inflammatory responses. The aim of this study is to evaluate the effect of ulinastatin on postoperative blood loss and laboratory changes in patients undergoing open heart surgery. MATERIALS AND METHODS: Between January 2008 and February 2009, 110 patients who underwent atrioventricular valve surgery through right thoracotomy were divided into two groups. Patients received either 5,000 U/kg ulinastatin (ulinastatin group, n=41) or the equivalent volume of normal saline (control group, n=69) before aortic cross clamping. The primary end points were early coagulation profile changes, postoperative blood loss, transfusion requirements, and duration of intubation and intensive care unit stay. RESULTS: There were no statistically significant differences between the two groups in early coagulation profile, other perioperative laboratory data, and postoperative blood loss with transfusion requirements. CONCLUSION: Administration of ulinastatin during operation did not improve the early coagulation profile, postoperative blood loss, or transfusion requirements of patients undergoing open heart surgery. In addition, no significant effect of ulinastatin was observed in major organs dysfunction, systemic inflammatory reactions, or other postoperative profiles.


Sujets)
Humains , Pontage cardiopulmonaire , Constriction , Glycoprotéines , Coeur , Hémostase , Unités de soins intensifs , Intubation , Granulocytes neutrophiles , Hémorragie postopératoire , Chirurgie thoracique , Thoracotomie , Trypsine
18.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 185-191, 2013.
Article Dans Anglais | WPRIM | ID: wpr-129685

Résumé

BACKGROUND: Cardiopulmonary bypass (CPB) induces variable systemic inflammatory reactions associated with major organ dysfunction via polymorphonuclear neutrophils (PMNs). Ulinastatin, a urinary trypsin inhibitor, inhibits PMN activity and reduces systemic inflammatory responses. The aim of this study is to evaluate the effect of ulinastatin on postoperative blood loss and laboratory changes in patients undergoing open heart surgery. MATERIALS AND METHODS: Between January 2008 and February 2009, 110 patients who underwent atrioventricular valve surgery through right thoracotomy were divided into two groups. Patients received either 5,000 U/kg ulinastatin (ulinastatin group, n=41) or the equivalent volume of normal saline (control group, n=69) before aortic cross clamping. The primary end points were early coagulation profile changes, postoperative blood loss, transfusion requirements, and duration of intubation and intensive care unit stay. RESULTS: There were no statistically significant differences between the two groups in early coagulation profile, other perioperative laboratory data, and postoperative blood loss with transfusion requirements. CONCLUSION: Administration of ulinastatin during operation did not improve the early coagulation profile, postoperative blood loss, or transfusion requirements of patients undergoing open heart surgery. In addition, no significant effect of ulinastatin was observed in major organs dysfunction, systemic inflammatory reactions, or other postoperative profiles.


Sujets)
Humains , Pontage cardiopulmonaire , Constriction , Glycoprotéines , Coeur , Hémostase , Unités de soins intensifs , Intubation , Granulocytes neutrophiles , Hémorragie postopératoire , Chirurgie thoracique , Thoracotomie , Trypsine
19.
Annals of Occupational and Environmental Medicine ; : 15-2013.
Article Dans Anglais | WPRIM | ID: wpr-100587

Résumé

OBJECTIVES: This research was conducted with an aim of determining the correlation between job insecurity and an employee's work-related health problems among permanent and temporary workers. METHODS: Using the data from the First Korean Working Conditions Survey conducted in 2006, a total of 7,071 workers, excluding employers and the self-employed, were analyzed. Work-related health problems were categorized as backache, headache, abdominal pain, muscular pain, stress, fatigue, insomnia, anxiety or depression. Each problem was then analyzed for its relationship to job insecurity through logistic regression analysis. RESULTS: Among the 7,071 workers, 5,294 (74.9%) were permanent workers and 1,777 (25.1%) were temporary workers. For the permanent workers, presence of high or moderate job insecurity appeared more closely linked to backache, headache, abdominal pain, muscular pain, stress, fatigue, insomnia, anxiety, and depression compared to absence of job insecurity. However, for the temporary workers, only depression appeared to be associated with the presence of high job insecurity. CONCLUSION: The study showed that the presence of job insecurity is correlated with work-related health problems. The deleterious effects of job insecurity appeared to be stronger in permanent than temporary workers. Additional research should investigate ways to effectively reduce job insecurity.


Sujets)
Douleur abdominale , Anxiété , Dorsalgie , Dépression , Fatigue , Céphalée , Modèles logistiques , Troubles de l'endormissement et du maintien du sommeil
20.
Intestinal Research ; : 300-304, 2012.
Article Dans Coréen | WPRIM | ID: wpr-45080

Résumé

Mantle cell lymphoma (MCL) is a subtype of B-cell non-Hodgkin's lymphoma (NHL), accounting for 3-10% of NHL. MCL involves the gastrointestinal (GI) tract in 10-30% of patients and common sites of MCL GI tract involvement are the colorectum and stomach, but any region of the GI tract may be involved. GI tract involvement by MCL usually presents in the form of multiple lymphomatous polyposis involving several segments of the GI tract. A few cases of MCL presenting with a GI tract stricture have been reported. Here, we present a rare case of a small intestinal stricture caused by MCL and review the literature of this disease.


Sujets)
Humains , Comptabilité , Lymphocytes B , Sténose pathologique , Tube digestif , Intestin grêle , Lymphome à cellules du manteau , Lymphome malin non hodgkinien , Estomac
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