Résumé
The purpose of the study is to analyze the impact of 9-week intensive aerobic exercises and the calcium and vitamin D supplement intake on the indicators which show bone formation in young women. 44 non-athletic women in their thirties [27.18 +/- 3.65] were studied randomly in four groups: 1] Exercise, 2] Calcium and vitamin D supplement, 3] Exercise and supplement, and 4] control. The subjects exercised three sessions a week for 9 weeks, each session lasted 30-45 minutes. The blood and urinary samples were collected from the experimental and control groups while they fasted either before or after exercise program. The concentration of alkaline phosphates and procollagen I, C terminal [PICP] had been measured using DGKC and HPLC techniques, respectively. The collected data had been combined with the statistical t-tests and were analyzed by ANCOVA [p<0.05]. Significant increasing of ALP and PICP was observed in exercise group [p=0.001] and exercise + supplement group [p=0.001]. In supplement group, alkaline phosphate and procollagen type 1, C-terminal show a significant decrease [p=0.001], while the difference was not significant in the control group. Generally, the research results show that the intensive aerobic exercise and adequate intake of calcium and vitamin D affect positively the bone mass development during youth and they reduce fracture risk; however, such claim needs further investigations
Résumé
The aim of this study was to determine the effect of 9 weeks aerobic exercise and multivitamin supplement on plasma level of HCY, CRP and TNF-alpha in non-athletic obese women. Total 30 sedentary and healthy obese women aged 25-50 year and BMI >/=30 Kg/m2 volunteered for this study. The subjects were randomly categorized into three experimental groups, aerobic group, aerobic-supplement group, and a nonintervention control group. The experimental groups went through a 9-week [3 days per week] aerobic exercise program. Blood samples were taken of all subjects before and after the aerobic exercise program at overnight fast. The data were analyzed through paired t test, ANOVA, and Dant. The significance level was p<0.05. Aerobic and aerobic-supplement exercise decreased the rate of HCY [p=0.013], CRP [p=0.001] and TNF-alpha [p=0.006] in obese women significantly, also the reduction of basic rates of CRP and TNF-alpha in aerobic group [p=0.001] and aerobic-supplement group [p=0.001] were significant compared to control group. But reduction of basic HCY levels was not significant, though. This reduction was significant in aerobic-supplement group [p=0.036]. This prospective data indicate that aerobic exercise with definitive intensity and multivitamin supplement decreased cardiovascular risk factors in obese women. Therefore as a modifiable lifestyle factor should be encouraged in obese adults for prevention of cardiovascular events