Résumé
Objective: In patients with chronic liver disease, determine the accuracy of portal vein diameter in the diagnosis of portal hypertension confirmed on Serum-Ascites Albumin Concentration Gradient
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted in the Department of Medicine at AbbasiShaheed Hospital, Karachi for a period of six months from January to June 2012
Materials and Methods: Seventy patients with decompensated CLD were included in this study. The routine testing of ascitic fluid was included total protein, albumin and cell count. All patients underwent ultrasonography of abdomen
Results: The average age of the patients was 48.97 +/- 7.52 years. 47[67.1%] were male and 23[32.9%] were female
In the diagnosis of portal hypertension confirmed by serum ascites albumin of decompensated chronic liver disease 95.7% positive accuracy of portal vein diameter was found
Conclusion: Our study of small predominantly male sample found a very high positive accuracy of portal vein diameter in determining portal hypertension. The results are similar to previous researches that have also shown a higher accuracy rates but slightly lower than our study
Résumé
Rats were intratracheally (i.t.) exposed to 36.5 or 27.5 microg of cadmium (Cd) as soluble cadmium chloride (CdCl2) and insoluble cadmium oxide (CdO) salts. The retention of metal in lungs, liver and kidney was assessed by atomic adsorption spectrophotometer. The animals were intraperitoneally (i.p.) primed with sheep red blood cells (SRBC) and assessed for the number of antibody forming cells in lung associated lymph nodes (LALN) and spleen. Both the compounds had similar retention of metal in lungs but CdO induced more pulmonary inflammatory and degradative changes than CdCl2. The larger influx of polymorphonuclear cells (PMNs) following CdO exposure appears to be due to the absence of protection afforded by Cd induced metallothionein cytoplasmic protein while the Cd metallothionein complex formed in the case of CdCl2 is more protective. However both forms of Cd had similar local immunosuppressive potential but CdO had more prolonged suppressive effect.