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1.
Pediatric Gastroenterology, Hepatology & Nutrition ; : 546-554, 2021.
Article Dans Anglais | WPRIM | ID: wpr-918681

Résumé

Purpose@#Malnutrition is a significant issue for pediatric patients with cancer. We sought to evaluate the effectiveness and complication rate of percutaneous endoscopic gastrostomy (PEG) placement in pediatric oncology patients. @*Methods@#A retrospective chart review was performed on 49 pediatric oncology patients undergoing PEG placement at Johns Hopkins All Children's Hospital between 2000 and 2016.Demographic and clinical characteristics, complications, absolute neutrophil count at time of PEG placement and at time of complications, length of stay, and mortality were identified.Weight-for-age Z-scores were evaluated at time of- and six months post-PEG placement. @*Results@#The overall mean weight-for-age Z-score improved by 0.73 (p<0.0001) from pre-(–1.11) to post- (–0.38) PEG placement. Improvement in Z-score was seen in patients who were malnourished at time of PEG placement (1.14, p<0.0001), but not in those who were not malnourished (0.32, p=0.197). Site infections were seen in 12 (24%), buried bumper syndrome in five (10%), and tube dislodgement in one (2%) patient. One patient (2%) with fever was treated for possible peritonitis. There were no cases of other major complications, including gastric perforation, gastrocolic fistula, clinically significant bleeding, or PEGrelated death documented. @*Conclusion@#Consistent with previous studies, our data suggests a relationship between site complications (superficial wound infection, buried bumper syndrome) and neutropenia.Additionally, PEG placement appears to be an effective modality for improving nutritional status in malnourished pediatric oncology patients. However, larger prospective studies with appropriate controls and adjustment for potential confounders are warranted to confirm these findings.

2.
Pediatric Gastroenterology, Hepatology & Nutrition ; : 619-623, 2019.
Article Dans Anglais | WPRIM | ID: wpr-760876

Résumé

We report the case of a seven-year-old boy with an ingested foreign body, which was retained within the appendix for a known duration of ten months, ultimately requiring appendectomy. The ingested foreign body was incidentally discovered by abdominal x-ray at an emergency room visit for constipation. Despite four bowel cleanouts, subsequent x-rays showed persistence of the foreign body in the right lower quadrant. While the patient did not have signs or symptoms of acute appendicitis, laparoscopic appendectomy was performed due to the risk of this foreign body causing appendicitis in the future. A small metallic object was found within the appendix upon removal. This case highlights the unique challenge presented by foreign body ingestions in non-verbal or developmentally challenged children and the importance of further diagnostic workup when concerns arise for potential retained foreign bodies.


Sujets)
Enfant , Humains , Mâle , Appendicectomie , Appendicite , Appendice vermiforme , Trouble du spectre autistique , Constipation , Service hospitalier d'urgences , Endoscopie , Corps étrangers , Gastroentérologie , Pédiatrie
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