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Chinese Journal of Experimental and Clinical Virology ; (6): 8-10, 2009.
Article Dans Chinois | WPRIM | ID: wpr-332446

Résumé

<p><b>OBJECTIVE</b>To investigate genotype of HCV infection among residents in a rural village, Hebei Province.</p><p><b>METHODS</b>Blood samples of the 520 residents were collected, and C/E1 of HCV genome of the 483 samples were obtained by RT-PCR amplifying, and the gene sequences were analyzed and the polygenetic tree were drawn by the software Mega 4.0.</p><p><b>RESULTS</b>In 483 subjects, HCV-RNA positive objectives are 70, positive prevalence is 14.5%, genotyping for all the samples successfully, including genotypes 1b and 2a, which are 36 (51.4%), 34 (48.6%) respectively.</p><p><b>CONCLUSION</b>HCV RNA positive rate is 14.5%, which is higher than general people. Subtypes 1b and 2a seemed to be the dominant genotypes of HCV in Zhao county area of Hebei Province.</p>


Sujets)
Adolescent , Adulte , Enfant , Enfant d'âge préscolaire , Femelle , Humains , Nourrisson , Nouveau-né , Mâle , Adulte d'âge moyen , Jeune adulte , Donneurs de sang , Chine , Épidémiologie , Génotype , Hepacivirus , Classification , Génétique , Hépatite C , Épidémiologie , Virologie , Données de séquences moléculaires , Phylogenèse
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