Case control study on risk factors of congenital microtia / 中华耳鼻咽喉头颈外科杂志

<p><b>OBJECTIVE</b>To identify the risk factors associated with congenital microtia.</p><p><b>METHODS</b>A case-control, retrospective study was performed. A total of 207 cases of congenital microtia and 209 age-frequently-matched controls were interviewed individually according to the uniform questionnaire. The questionnaire included: (1) Essential information about patients and their parents. (2) First trimester diseases and medication of mother. (3) Past gestation history of mother. (4) Family history and life style of the parent. The available data were analyzed by chi-square test and multivariate Logistic regression model.</p><p><b>RESULTS</b>The factors, such as gender (OR = 5.893), first trimester disease of mother (OR = 34.49) and medication (OR = 4.299), excessive drinking and smoking of father (OR = 4. 347, OR = 4.304), non-primiparous parity (OR = 9.524), abortion (spontaneous and induced, OR = 1.723), low-education of mother (OR = 2.275) were risk factors contributing to microtia in multivariate study. The factors, such as tea (OR = 0.179) were protective factors in multivariate study.</p><p><b>CONCLUSIONS</b>Multi-risks factors are contributing to microtia. Preventive measures according to risk factors should be put forward.</p>

Psychologic status and their influencing factors in congenital microtia patients and their families / 中华整形外科杂志

<p><b>OBJECTIVE</b>To study the psychologic status and their influencing factors in congenital microtia patients and their families.</p><p><b>METHODS</b>Totally one hundred and two congenital microtia patients (79 men, 23 women, mean age 13.62 +/- 7.2 years) were enrolled. The patients and their families answered the questionnaire written by ourselves to identify the psychosocial problems.</p><p><b>RESULTS</b>(1) 23.5% patients were found to have severe psychosocial problems, such as lack of self-confidence, close and fear and so on. (2) With the growth of age, psychosocial problems of the patients were rated high (P < 0.05). (3) For patients who found their deformations early, psychosocial problems also were rated low. (4) For patients who found their deformations by themselves, psychosocial problems also were rated low. (5) The education and psychosocial impact for parents all affected patients deeply.</p><p><b>CONCLUSIONS</b>To prevent psychosocial problems, we should operate for patients as early as possible. And correct guidance is very important for youngsters.</p>