Advances in pertussis toxin detoxification / 中华微生物学和免疫学杂志

Pertussis toxin (PT) is one of the major virulence factors of Borrelia pertussis and also an essential component of pertussis vaccines. Before using it in vaccine production, detoxification is necessa-ry because of its biological activity. This paper summarized the structure and detoxification process of PT as well as the safety and immunogenicity of pertussis vaccines prepared with detoxified PT.

Effects of nonbacterial inflammatory stimulus to prostate on bladder functions in rats / 第三军医大学学报

0.05), but changed to be significant after stimulation in the rats stimulated respectively with formalin and saline (P