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Objective:To analyze the medication law of TCM oral prescriptions in the treatment of postherpetic neuralgia (PHN).Methods:The effective cases and clinical studies about TCM oral prescriptions in the treatment of PHN were retrieved from CNKI, Wanfang Data, VIP, and CBM from January 1, 2002 to December 31, 2021. The medication frequency and drug properties were counted through the Ancient and Modern Medical Record Cloud Platform, and correlation analysis, cluster analysis and complex network analysis were performed.Results:A total of 233 articles were included, involving 243 prescriptions and 191 kinds of Chinese materia medica. There were 20 kinds of Chinese materia medica with frequency >40, most of which have the efficacy of promoting blood circulation to remove blood stasis. The Chinese materia with heat-clearing and detoxifying efficacy were also often used. The properties were mainly warm, mild, slight cold, and cold, tastes were mainly bitter, pungent and sweet, and meridians were mainly liver, spleen and heart meridians. The association rule analysis was used to obtain 15 commonly used TCM groups. The commonly used Chinese materia medica could be clustered into 4 categories. The core prescription obtained by complex network analysis was Angelicae Sinensis Radix, Glycyrrhizae Radix et Rhizoma, Corydalis Rhizoma, Bupleuri Radix, Carthami Flos, Paeoniae Radix Alba, Persicae Semen, Chuanxiong Rhizoma, and Rehmanniae Radix.Conclusion:TCM oral prescriptions for the treatment of PHN put promoting blood circulation to remove blood stasis and activating meridians to stop pain in priority, taking into account the clearing heat, regulating qi and blood.
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Objective This paper explores the application effects of the teaching mode of"Problem-based Learning (PBL)" in Chinese internal medicine teaching. Methods 73 students from the major of traditional Chinese medicine from the First Clinical Medical College of Shandong University of Traditional Chinese Medicine are divided into observation group(36)and control group(37)with the random number table. Two different teaching methods, i.e., PBL and LBL (Lecture Based Learning), are employed to carry out prospective and randomized controlled study at parallel level, and then questionnaire are used to evaluate the teaching effects. Results The average scores of the observation group are high than those of the controlled group in the following aspects:the active classroom atmosphere(3.5 ± 0.6 vs.3.2 ± 0.6,t=2.275),improving classroom attention(3.6 ± 0.6 vs.3.2 ± 0.7,t=2.778),benefiting to the grasping of knowledge(3.5 ± 0.6 vs.3.0 ± 0.6,t=2.818), improving the self-taught ability(3.6 ± 0.6 vs.3.0 ± 1.1,t=2.935),improving the ability of analyzing problems(3.7 ± 0.5 vs. 3.1 ± 1.0, t=3.072), improving TCM thinking ability (3.5 ± 0.6 vs. 3.1 ± 0.9, t=2.431), enhancing the cooperative ability(3.6 ± 0.6 vs.3.0 ± 1.0,t=3.049),improving the communication ability(3.7 ± 0.5 vs.3.0 ± 1.0, t=3.864)and improving the innovation consciousness(3.2 ± 0.7 vs.2.7 ± 0.9,t=2.423)(P<0.05 or P<0.01).The score of the comprehensive evaluation of the questionnaire in the observation group are higher than that in the controlled group (P<0.01). Conclusions PBL teaching method has remarkable advantages over LBL teaching method in training the knowledge, ability and quality of students, as well as the overall teaching effect.
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Objective To explore the rule of acupoints selection of acupuncture and moxibustion in treating Alzheimer disease based on TCM Knowledge Service and Sharing System (V1.2.8); To provide references for the clinic. Methods Literature about acupuncture and moxibustion for the treatment of Alzheimer disease in CNKI, Choingqing Weipu, Wanfang database, and CBM from 1st January, 1996 to 1st January, 2016 was searched. Excel2007 was used to establish database and enter into TCM Knowledge Service and Sharing System (V1.2.8). The data were analyzed by data mining method such as frequency analysis, association rule analysis, point-to-pair analysis and core prescription analysis. Results After screening, 125 acupuncture prescriptions were included, involving 108 acupoints and 998 total acupoints selection frequency. Baihui had the highest frequency (78 times, 62.40％). The core acupoint combinations were Zusanli-Baihui, Zusanli-Sanyinjiao, and Baihui-Sishencong. The main core prescription was Bauhui, Zusanli, Sishencong, Shenmen, Taixi, Sanyinjiao, Neiguan, Taichong, Fenglong, Dazhui, Fengchi, Shenshu, Shenting, Xuanzhong. The second core prescription was Hegu, Yintang, Tanzhong, Xuehai, Geshu, Ganshu, Pishu, Qihai, Yanglingyuan, and Shangxing. Conclusion The rules of acupoints selection analyzed by TCM Knowledge Service and Sharing System (V1.2.8) for Alzheimer disease can be used to guide clinical application, but with modification according to symptoms.
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Objective Applyingthe traditional Chinese medical knowledge service and sharing system, to explore the medication rules of ankylosing spondylitis in the medical records.Methods The ankylosing spondylitis medical records in the traditional chinese medical knowledge service and sharing system has been searched and 149 prescriptions were identified. The medication frequency, association rules, herbal combination and the cluster analyses were explored.Results Among the 149 prescriptions with 210 drugs, the use of high frequency drugs wereGouji, Baishao, Danggui, Duzhong, Weilingxian, and other medication whose frequency was more than 20 times were good at tonifying liver and kidney, activating blood circulation, clearing heat and promoting diuresis, dispelling cold and removing dampness. The high frequency of drug combinations included Sangjisheng and Gouji, Duzhong and Gouji, Baishao and Gouji, Guizhi and Baishao, Gancao and Danggui.Conclusions The treatment of ankylosing spondylitis with Chinese medicine is mainly based on tonifying liver and kidney, supplemented with drugs for warming Kidney Yang, dispelling cold and dehumidification, promoting blood circulation and removing blood stasis, clearing heat and promoting diuresis, dispelling wind and cold.
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Objective To discuss the relationship of blood trace elements and children with recurrent respiratory infection in the lung-spleen-qi-deficiency, spleen-deficiency-hyperactive-liver-fire types.[Methods] Select 150 children with recurrent respiratory tract infection in the lung-spleen-qi-deficiency, and 150 children in the spleen-deficiency-hyperactive-liver-fire. Checking serum blood zinc, iron, calcium, magnesium, copper levels in both groups. Select 220 normal children in out-patient physical examination in the same period.[Results] Blood zinc, iron, calcium content of two syndromes of traditional Chinese medicine was significantly lower than those of healthy children in the control group. Compared with the two Chinese medicine syndromes, zinc, iron, calcium, magnesium, copper, there were no significant differences between them. [Conclusion]Children with recurrent respiratory infection exist a lack of trace elements, the syndromes of traditional Chinese medicine and trace elements are not positive, negative correlation.
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[Objective]To summarize Pro.YangJiguo’s experience in using PingchuanⅠ for treating three periods of asthma in children .[Method] Accord-ing to the analysis of three clinical features and diagnosis and treatment of pediatric asthma, namely attack period(not the control period), duration peri-od(part of the control period) and remission period(control period), it concluded Professor Yang Jiguo's how to use PingchuanⅠto treat pediatric asthma. [Result] For pediatric asthma episodes in smooth wheezing, we join the medicine of freeing lung to relieve exterior syndrome on the basis of Pingchuan I;in duration, join yupinfeng for nourishing Qi and supporting essence; in remission, join the dragon negundo ginseng and astragalus mixture to improve children's physique, and improve the body's immune function. [Conclusion] Pingchuan I for treating three periods of asthma in children has a significant effect, unique advantages and is worth promotion.