Research progress on antitumor activities of C21 steroidal glycosides of Cynanchi Bungei Radix / 中草药

Cynanchi Bungei Radix is a precious Chinese meteria medica of tonifying kidney, benefiting liver, keeping fit, and preventing senility, which also has the pharmacological effect of cancer prevention and anticancer. C21 steroids glycosides are considered as one of its main anticancer active components. In this paper, the main types of C21 steroids and glycosyl groups, the main antitumor mechanism of C21 steroidal glycosides, the effect of C21 steroidal glycosides on different tumors and the influencing factors, and the toxicological research status of C21 steroidal glycosides were reviewed, which can provide references for the following research of C21 steroidal glycosides in Cynanchi Bungei Radix.