Application of endoscopic retrograde cholangiopancreatology in pediatric chronic pancreatitis / 中华实用儿科临床杂志

Chronic pancreatitis is a focal or diffuse chronic inflammation and fibrosis of pancreatic tissue, which is progressive, persistent and irreversible.Chronic pancreatitis in children has its own characteristics of early onset and frequent occurrence, which greatly affects the nutritional status and quality of life of children.Recently, diagnosis and treatment of this severe inflammation gradually improved with a burgeoning technique: endoscopic retrograde cholangiopancreatography (ERCP), especially in the treatment of pediatric chronic pancreatitis.The detection rate of the disease has been increasing year by year.As an effective and safe procedure for the treatment of chronic pancreatitis in children, ERCP has replaced traditional surgery and become the first-line treatment method for pediatric chronic pancreatitis.

The research on two different algorithms used in generating MLC fields of IMRT plan / 中国医疗器械杂志

<p><b>PURPOSE</b>To validate that DMPO model for "one step" algorithm can reduce the total MLC segments number, we compare the dosage distribution of "one-step" algorithm with "two-step" algorithm for generating IMRT MLC segments.</p><p><b>METHODS</b>On the platform of "Pinnacle 8.0h" version radiation treatment planning system developed by Philips, we respectively select one head and neck tumor case, one thorax tumor case and one abdomen tumor case, by means of designing seven fields IMRT planning, then utilized "one-step" algorithm and "two-step" algorithm to optimize and generate IMRT MLC segments, and then calculated dosage distribution, evaluated dosage distribution lines and DVH diagram, in order to compare the two MLC segment groups generated by the two different algorithm.</p><p><b>RESULT</b>For the three IMRT plans selected by us, the number of MLC segments generated by "two-step" algorithm appear to be larger than "one-step" algorithm but dosage distribution seems to be worse than the latter.</p><p><b>DISCUSSION</b>For utilizing the "Pinnacle" plan system to design IMRT plan, "one-step" algorithm with "DMPO" definitely can effectively reduce the number of MLC segments, what's more, the result of dosage distribution seems to be better.</p>