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Objective To explore the correlation of of lymph node metastasis rate ( LR) with postoperative recurrence and prognosis in patients with thyroid papillary carcinoma (PTC). Methods From January 2010 to June 2013,the clinical data of sixty-two patients with PTC in Baoshan Branch,Shanghai First People′s Hospital were retrospectively analyzed. According to the LR, patients were divided into low LR (＜25%) group(38 cases),high LR(≥25%) group (24 cases). The clinical pathological characteristics, postoperative recurrence and 5-year survival rate of the two groups was compared,and the influence factors of prognosis were analyzed. Results There was significant difference in LR among patients with different ages,numbers of lesions,lesion diameters,TNM stages and numbers of lymph node metastasis (P＜0. 05);compared with high LR group,the recurrence in low LR group was obviously reduced(15. 8% vs. 41. 7%), and 5-year survival rate was significantly increased ( 92. 1% vs. 63. 0%) ( P＜0. 05) . LR and TNM stage were the independent risk factors of prognosis in PTC patients,and age was independent protection factor (HR＝1. 587,1. 714,0. 617,P＜0. 05). Conclusion LR can be used as one of postoperative recurrence and prognosis evaluation indicators of PTC.
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Objective To investigate the efficacy of different treatments for breast ductal carcinoma in situ. Methods From January 2010 to March 2015,a total of seventy-eight patients with intraductal carcinoma in Shanghai First People's Hospital Baoshan Branch were enrolled in the study. According to the different treatment methods,the patients were divided into the experimental group (33 cases) and control group (45 cases). The experimental group was given breast conserving surgery plus adjuvant radiotherapy,while the control group was treated with modified radical operation. The operative time, intraoperative blood loss, drainage volume and hospital stay were compared between the two groups. The survival and adverse events of the two groups were analyzed. Results The hospitalization time (( 8. 13 ± 3. 43) d), operation time (( 108. 56 ± 22. 27) min), intraoperative blood loss ((78. 72±30. 74) ml) and drainage ((259. 68±35. 95) ml) in observation group were significantly shorter than those in the control group ((15. 56±2. 73)d,(148. 62±23. 85) min,(169. 28±26. 33) ml,(553. 37 ± 45. 64) ml) The difference between the two groups was statistically significant ( t＝12. 160, 9. 378,17. 304,38. 265,P＜0. 05). Log-rank test showed that the good prognosis rate of two groups in 24 months was 90. 32% and 88. 64% respectively,the difference was not statistically significant ( x 2＝1. 246,P＞0. 05) . Conclusion Breast conserving surgery plus adjuvant radiotherapy is the first choice for the treatment of breast ductal carcinoma in situ.
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0.05 ), the postoperative complication and mortality rate of PG group were 13.7% and 6.8%, of TG group was all 6%.Conclusions:Proximal and total gastrectomy treatment does not significantly influence the prognosis of patients with cardia and esophgogastric junction cancer in progressive stage.