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1.
Blood Research ; : 83-90, 2023.
Article Dans Anglais | WPRIM | ID: wpr-999728

Résumé

Background@#The goal of induction therapy for multiple myeloma (MM) is to achieve adequate disease control. Current guidelines favor triplet (bortezomib-lenalidomide-dexamethasone;VRd) or quadruplet regimens (daratumumab, bortezomib-thalidomide-dexamethasone;D-VTd). In the absence of a direct comparison between two treatment regimens, we conducted this study to compare the outcomes and safety of VRd and D-VTd. @*Methods@#Newly diagnosed MM patients aged >18 years who underwent induction therapy followed by autologous stem cell transplantation (ASCT) between November 2020 and December 2021 were identified. Finally, patients with VRd (N=37) and those with D-VTd (N=43) were enrolled. @*Results@#After induction, 10.8% of the VRd group showed stringent complete remission (sCR), 21.6% showed complete response (CR), 35.1% showed very good partial response (VGPR), and 32.4% showed partial response (PR). Of the D-VTd group, 9.3% showed sCR, 34.9% CR, 48.8% VGPR, and 4.2% PR (VGPR or better: 67.6% in VRd vs. 93% in D-VTd, P =0.004). After ASCT, 68.6% of the VRd group showed CR or sCR, while 90.5% of the D-VTd group showed CR or sCR (P=0.016). VRd was associated with an increased incidence of skin rash (P=0.044). Other than rashes, there were no significant differences in terms of adverse events between the two groups. @*Conclusion@#Our study supports the use of a front-line quadruplet induction regimen containing a CD38 monoclonal antibody for transplant-eligible patients with newly diagnosed MM.

2.
Blood Research ; : 184-192, 2017.
Article Dans Anglais | WPRIM | ID: wpr-185280

Résumé

BACKGROUND: Isolated myeloid sarcoma (MS) is a rare extramedullary tumor mass composed of malignant myeloid precursor cells without any evidence of leukemia in the peripheral blood and bone marrow. We describe the clinical characteristics and outcomes of patients diagnosed with isolated MS at our institution. METHODS: We retrospectively reviewed 9 of 497 acute myeloid leukemia (AML) patients (1.8%) with isolated MS. Isolated MS patients were divided into 2 groups according to the first-line treatment strategy: systemic treatment only (S) or local treatment with or without systemic treatment (LS). RESULTS: The most common site of MS occurrence was the head and neck area (N=4, 44.4%), followed by the anterior mediastinum (N=2, 22.2%) and the gastrointestinal tract (N=2, 22.2%). The tumors of 4 patients (44.4%) eventually evolved to AML, in a median time of 13.4 months (range, 2.4–20.1 mo). The number of patients achieving complete remission after first-line treatment was higher in the LS group (N=5, 83.3%) than in the S group (N=1, 33.3%) (P =0.226). All patients in the LS group survived, but those in the S group died (P=0.012). CONCLUSION: Accurate and rapid diagnosis using various modalities and the early initiation of intensive combined treatment may be the optimal strategies to reduce the risk of isolated MS subsequently evolving to AML. To fully understand the characteristics of isolated MS, a larger number of patients from a multinational study is necessary.


Sujets)
Humains , Moelle osseuse , Diagnostic , Tube digestif , Tête , Leucémies , Leucémie aigüe myéloïde , Médiastin , Cou , Études rétrospectives , Sarcome myéloïde
3.
Journal of Korean Medical Science ; : 510-518, 2016.
Article Dans Anglais | WPRIM | ID: wpr-122520

Résumé

The aim of this study was to identify the risk factors associated with severe bacterial infection (SBI) in multiple myeloma (MM) patients during treatment with bortezomib-based regimens. A total of 98 patients with MM were evaluated during 427 treatment courses. SBI occurred in 57.1% (56/98) of the patients and during 19.0% (81/427) of the treatment courses. In the multivariate analysis for the factors associated with the development of SBI in each treatment course, poor performance status (Eastern Cooperative Oncology Group ≥ 2, P < 0.001), early course of therapy (≤ 2 courses, P < 0.001), and pretreatment lymphopenia (absolute lymphocyte count < 1.0 × 10(9)/L, P = 0.043) were confirmed as independent risk factors. The probability of developing SBI were 5.1%, 14.9%, 23.9% and 59.5% in courses with 0, 1, 2, and 3 risk factors, respectively (P < 0.001). In conclusion, we identified three pretreatment risk factors associated with SBI in each course of bortezomib treatment. Therefore, MM patients with these risk factors should be more closely monitored for the development of SBI during bortezomib-based treatment.


Sujets)
Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Protocoles de polychimiothérapie antinéoplasique/usage thérapeutique , Infections bactériennes/complications , Bortézomib/administration et posologie , Bactéries à Gram négatif/isolement et purification , Bactéries à Gram positif/isolement et purification , Numération des lymphocytes , Lymphopénie/thérapie , Myélome multiple/complications , Analyse multifactorielle , Modèles des risques proportionnels , Études rétrospectives , Facteurs de risque , Transplantation de cellules souches , Taux de survie , Transplantation homologue
4.
Tuberculosis and Respiratory Diseases ; : 121-126, 2016.
Article Dans Anglais | WPRIM | ID: wpr-197495

Résumé

Lung function reportedly declines with age and that this decline is accelerated during disease progression. However, a recent study showed that the decline might peak in the mild and moderate stage. The prognosis of chronic obstructive pulmonary disease (COPD) can be improved if the disease is diagnosed in its early stages, prior to the peak of decline in lung function. This article reviews recent studies on early COPD and the possibility of applying the U.S. Preventive Services Task Force recommendation 2008 and 2015 for early detection of COPD in Korea.


Sujets)
Comités consultatifs , Évolution de la maladie , Diagnostic précoce , Directives de santé publique , Corée , Poumon , Pronostic , Broncho-pneumopathie chronique obstructive
5.
Journal of Korean Medical Science ; : 553-560, 2016.
Article Dans Anglais | WPRIM | ID: wpr-58427

Résumé

The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and university-affiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George's Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean post-bronchodilator FEV1 was 55.8% ± 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies.


Sujets)
Sujet âgé , Femelle , Humains , Mâle , Adulte d'âge moyen , Études de cohortes , Comorbidité , Dépression/épidémiologie , Diabète/épidémiologie , Dyspnée/complications , Volume expiratoire maximal par seconde , Hôpitaux universitaires , Hypertension artérielle/épidémiologie , Poumon/physiopathologie , Broncho-pneumopathie chronique obstructive/complications , Qualité de vie , République de Corée , Tests de la fonction respiratoire , Indice de gravité de la maladie , Sociétés médicales , Enquêtes et questionnaires , Centres de soins tertiaires , Test de marche
6.
Annals of Surgical Treatment and Research ; : 147-156, 2016.
Article Dans Anglais | WPRIM | ID: wpr-220407

Résumé

PURPOSE: This retrospective study was an investigation of overall survival (OS), disease-free survival (DFS) and prognostic factors affecting OS and DFS in cirrhotic patients who received intraoperative radiofrequency ablation (IORFA). METHODS: Between April 2009 and November 2013, 112 patients (94 men, 84%; 18 women, 16%) underwent IORFA for 185 cases of hepatocellular carcinomas (HCC). Repeat IORFA was done in 9 patients during the same period (total of 121 treatments). RESULTS: All patients were followed-up for at least 12 months (mean follow-up, 32 months). Surgical resection combined with IORFA was performed in 20 patients. The technical effectiveness at 1 week was 91.78% (111 of 121). Readmission was 9.1% (11 of 121) and the most common cause was ventral hernia. Procedure-related mortality was 2.7% (3 of 112) and continued fatal biliary leakage was 1.8% (2 of 112). Local recurrence developed in 10 patients (8.9%). Most recurrence was intrahepatic. Cumulative survival was assessed in 33 patients who received IORFA as primary treatment (naive patients) and 79 non-naive patients. The cumulative DFS and OS rate at l and 3 years was 54% and 24%, and 87% and 66%, respectively. Moderate ascites (P = 0.001), tumor located segment I (P = 0.001), portal vein thrombosis (P = 0.001) had poor survival were significant factors by multivariate analysis. CONCLUSION: IORFA alone or in combination with surgical resection extends the spectrum of liver surgery. A fundamental understanding of RFA, additional comorbidities, and postablation complication are necessary to maximize the safety and efficacy of IORFA for treating HCC with cirrhosis.


Sujets)
Femelle , Humains , Mâle , Ascites , Carcinome hépatocellulaire , Ablation par cathéter , Comorbidité , Survie sans rechute , Fibrose , Études de suivi , Hernie ventrale , Foie , Mortalité , Analyse multifactorielle , Récidive , Études rétrospectives , Thrombose veineuse
7.
Journal of Korean Medical Science ; : 1069-1074, 2016.
Article Dans Anglais | WPRIM | ID: wpr-13356

Résumé

Education has been known to essential for management of chronic airway diseases. However the real benefits remain unclear. We evaluated the effectiveness of an organized educational intervention for chronic airway diseases directed at primary care physicians and patients. The intervention was a 1-month education program of three visits, during which subjects were taught about their disease, an action plan in acute exacerbation and inhaler technique. Asthma control tests (ACT) for asthma and, chronic obstructive pulmonary disease (COPD) assessment tests (CAT) for COPD subjects were compared before and after education as an index of quality of life. Educational effectiveness was also measured associated with improvement of their knowledge for chronic airway disease itself, proper use of inhaler technique, and satisfaction of the subjects and clinicians before and after education. Among the 285 participants, 60.7% (n = 173) were men and the mean age was 62.2 ± 14.7. ACT for asthma and CAT in COPD patients were significantly improved by 49.7% (n = 79) and 51.2% (n = 65) more than MCID respectively after education (P < 0.05). In all individual items, knowledge about their disease, inhaler use and satisfaction of the patients and clinicians were also improved after education (P < 0.05). This study demonstrates the well-organized education program for primary care physicians and patients is a crucial process for management of chronic airway diseases.


Sujets)
Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Asthme/anatomopathologie , Prise en charge de la maladie , Connaissances, attitudes et pratiques en santé , Nébuliseurs et vaporisateurs , Éducation du patient comme sujet , Satisfaction des patients , Soins de santé primaires , Broncho-pneumopathie chronique obstructive/anatomopathologie , Qualité de vie , Respiration
8.
The Korean Journal of Internal Medicine ; : 132-132, 2015.
Article Dans Anglais | WPRIM | ID: wpr-208453

Résumé

This article would need the correction. We apologize for any inconvenience that this may have caused.

9.
Journal of Korean Medical Science ; : 725-732, 2015.
Article Dans Anglais | WPRIM | ID: wpr-146127

Résumé

The aim of the study was to evaluate the prevalence of restrictive ventilatory defect and to determine the risk factors in subjects with spirometrically-defined restrictive ventilatory defect. We used the population-based, fourth-2, 3 (2008, 2009) and fifth (2010-2012) Korea National Health and Nutrition Examination Survey (KNHANES) to analyze 15,073 subjects, aged > or =40 yr who underwent spirometry. Chest radiographs were also analyzed to identify restrictive lung disease. Spirometrically-defined restrictive ventilatory defect (FEV1/FVC> or =70% and FVC or =40 yr. The prevalence increased to 12.3% on using the lower limit of normal (LLN) criteria. Approximately 99.4% of subjects were classified as mild restrictive. Among these, 11.3% had inactive tuberculosis (TB) lesion, 2.2% cardiac disease, 2.0% previous operation scar or radiation injury and/or mediastinal disease, and 7.4% other pulmonary disease suggestive of restrictive lung diseases on chest radiograph. Evidence of previous TB history was independently associated with restrictive ventilatory defect (odds ratios [OR], 1.78; 95% confidence interval, 1.45-2.18) after adjustment for gender, age, smoking, area for residence and body mass index. The prevalence of restrictive ventilatory defect among the nationwide population in Korea was 11.3% with fixed ratio criterion and 12.3% with LLN criterion. Most cases were of the mild restrictive category and previous TB history is the independent risk factor for restrictive ventilatory defect.


Sujets)
Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Répartition par âge , Niveau d'instruction , Enquêtes sur les soins de santé , Logement , Revenu , Bronchopneumopathies obstructives/diagnostic , Prévalence , Reproductibilité des résultats , République de Corée/épidémiologie , Facteurs de risque , Sensibilité et spécificité , Répartition par sexe , Fumer/épidémiologie , Spirométrie/statistiques et données numériques
10.
Tuberculosis and Respiratory Diseases ; : 363-365, 2015.
Article Dans Anglais | WPRIM | ID: wpr-20107

Résumé

A 57-year-old male patient was admitted to our center because of a cystic mass on the lower portion of the right major fissure that was found incidentally by chest X-ray. He did not have a history of trauma or anticoagulant use. The lesion was removed by video-assisted thoracoscopic surgery. Pathological examination revealed an organizing pulmonary hematoma without any complications, and a follow-up chest X-ray after 1 year showed no recurrence.


Sujets)
Humains , Mâle , Adulte d'âge moyen , Études de suivi , Hématome , Récidive , Chirurgie thoracique vidéoassistée , Thorax
11.
The Korean Journal of Internal Medicine ; : 269-269, 2015.
Article Dans Anglais | WPRIM | ID: wpr-93724

Résumé

Results part of abstract has some error.

12.
Korean Journal of Medicine ; : 243-248, 2015.
Article Dans Anglais | WPRIM | ID: wpr-102974

Résumé

Post-transplant lymphoproliferative disorder (PTLD) is a spectrum of clinically and morphologically heterogeneous lymphoid proliferations of various clonal compositions that are observed after hematopoietic stem cell transplantation (HSCT) or solid organ transplantation. The majority of PTLD cases are associated with Epstein-Barr virus (EBV) infection, while overt peripheral blood (PB) or bone marrow (BM) involvement in PTLD is uncommon in early lesions. We report a 38-year-old woman with EBV-related PTLD, with BM and PB involvement, who presented with peripheral lymphocytosis as an early lesion 1 month after haploidentical HSCT for Philadelphia chromosome-positive acute lymphoblastic leukemia was performed during first complete remission. Although PB or BM involvement of PTLD after HSCT is uncommon in early lesions, peripheral lymphocytosis can be an initial presenting manifestation of PTLD, as in this case.


Sujets)
Adulte , Femelle , Humains , Moelle osseuse , Infections à virus Epstein-Barr , Transplantation de cellules souches hématopoïétiques , Herpèsvirus humain de type 4 , Lymphocytes , Hyperlymphocytose , Syndromes lymphoprolifératifs , Transplantation d'organe , Leucémie-lymphome lymphoblastique à précurseurs B et T , Transplantation , Transplants
13.
The Ewha Medical Journal ; : 131-135, 2014.
Article Dans Anglais | WPRIM | ID: wpr-80976

Résumé

Among the possible venous thromboembolic events in nephrotic syndrome, renal vein thrombosis and pulmonary embolism are common, while portal vein thrombosis (PVT) is rare. This report describes a 26-year-old man with histologically proven minimal change disease (MCD) complicated by PVT. The patient presented with epigastric pain and edema. He had been diagnosed with MCD five months earlier and achieved complete remission with corticosteroids, which were discontinued one month before the visit. Full-blown relapsing nephrotic syndrome was evident on laboratory and clinical findings, and an abdominal computed tomography revealed PVT. He immediately received immunosuppressants and anticoagulation therapy. An eight-week treatment resulted in complete remission, and a follow-up abdominal ultrasonography showed disappearance of PVT. In conclusion, PVT is rare and may not be easily diagnosed in patients with nephrotic syndrome suffering from abdominal pain. Early recognition of this rare complication and prompt immunosuppression and anticoagulation therapy are encouraged to avoid a fatal outcome.


Sujets)
Adulte , Humains , Douleur abdominale , Hormones corticosurrénaliennes , Anticoagulants , Oedème , Issue fatale , Études de suivi , Immunosuppression thérapeutique , Immunosuppresseurs , Néphrose lipoïdique , Syndrome néphrotique , Protéinurie , Embolie pulmonaire , Veines rénales , Thrombose , Échographie , Thrombose veineuse
14.
Tuberculosis and Respiratory Diseases ; : 227-229, 2014.
Article Dans Anglais | WPRIM | ID: wpr-92626

Résumé

Segniliparus species is a novel genus that is reported to be the new emerging respiratory pathogens. Here, we report a very rare case of S. rugosus pulmonary infection in an immunocompetent patient with non-cystic fibrosis. The organism was identified by 16S rRNA gene sequencing. The patient was successfully treated with antibiotics.


Sujets)
Humains , Antibactériens , Fibrose , Gènes d'ARN ribosomique , Mycobactéries non tuberculeuses , Infections de l'appareil respiratoire , Analyse de séquence d'ARN
15.
The Korean Journal of Internal Medicine ; : 764-773, 2014.
Article Dans Anglais | WPRIM | ID: wpr-126099

Résumé

BACKGROUND/AIMS: This study was conducted to assess the disease burden of pneumonia according to age and presence of underlying diseases in patients admitted with community-acquired pneumonia (CAP). METHODS: We performed a retrospective, observational study and collected data targeting patients with CAP (> or = 50 years) from 11 hospitals. Disease burden was defined as total per-capita medical fee, severity (CURB-65), hospital length of stay (LOS), and mortality. RESULTS: Of the 693 enrolled subjects, elderly subjects (age, > or = 65 years) had a higher mean CURB-65 score (1.56 vs. 0.25; p < 0.01) and higher mortality than nonelderly subjects (4.4% [n = 21] vs. 0.5% [n = 1]; p = 0.00). In addition, the total cost of pneumonia treatment was higher in elderly patients compared to in nonelderly patients (KRW 2,088,190 vs. US $1,701,386; p < 0.01). Those with an underlying disease had a higher CURB-65 score (1.26 vs. 0.68; p < 0.01), were much older (mean age, 71.24 years vs. 64.24 years; p < 0.01), and had a higher mortality rate than those without an underlying disease (3.5% [n = 20] vs. 1.7% [n = 2]; p = 0.56). Total per-capita medical fees were higher (KRW 2,074,520 vs. US $1,440,471; p < 0.01) and hospital LOS was longer (mean, 8.38 days vs. 6.42 days; p < 0.01) in patients with underlying diseases compared to those without. CONCLUSIONS: Due to the relatively high disease burden in Korea, particularly in the elderly and in those with an underlying disease, closer and more careful observation is needed to improve the outcomes of patients with CAP.


Sujets)
Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Répartition par âge , Facteurs âges , Infections communautaires/diagnostic , Comorbidité , Coûts et analyse des coûts , Coûts des soins de santé , Hospitalisation , Durée du séjour , Pneumopathie infectieuse/diagnostic , République de Corée/épidémiologie , Études rétrospectives , Appréciation des risques , Facteurs de risque , Indice de gravité de la maladie , Facteurs temps
16.
Journal of Minimally Invasive Surgery ; : 15-20, 2013.
Article Dans Coréen | WPRIM | ID: wpr-225322

Résumé

PURPOSE: Laparoscopic surgery has recently shown rapid development, and has been applied in most abdominal surgeries. It has also been adopted in hepatobiliary surgery, especially in the resection of liver tumors. Significant advantages of laparosopic surgery over the conventional open method have been reported, however, the safety of the surgical resection margin and radicality of the tumor resection remain to be clarified. This study was conducted in order to assess the feasibility and potential superiority of laparoscopic liver resection of hepatocellular tumors to open surgery. METHODS: This study included 76 patients who underwent liver resection for hepatocellular carcinoma at Dong-A University Hospital from January 2008 through June 2010. Of these 63 cases, 31 patients underwent laparoscopic resections and 33 underwent open liver resections. Both groups were confirmed as hepatocellular carcinoma by postoperative pathology and analyzed retrospectively. RESULTS: There were no statistically significant differences in preoperative parameters, such as age, height, body weight, Child Pugh score, ASA, and tumor size in both groups. There were no significant differences in operating time, duration of hospital stay, safety margins of surgical resection, postoperative complications, and rate of recurrence and occurrence of new lesions in both groups, however, better disease free survival was observed in the laparoscopic group (p=0.024). CONCLUSION: Findings of this study showed that the laparoscopic group had better results in free survival period than the open group. Conduct of larger scale prospective studies wound confirm the superiority of the laparoscopic liver resection to the conventional open procedure in patients with hepatocellular carcinoma. Findings of this study also suggest that assessment of the factors associated with the quality of life, such as degree of postoperative pain, and size of the incisional scar, and long term postoperative complications may play an additional role in favoring the laparoscopic liver resection. To elucidate the superiority of the laparoscopic liver resection to the conventional open method, conduct of study involving a larger study group and a longer prospective research period will be needed.


Sujets)
Enfant , Humains , Taille , Carcinome hépatocellulaire , Cicatrice , Survie sans rechute , Laparoscopie , Durée du séjour , Foie , Douleur postopératoire , Complications postopératoires , Qualité de vie , Récidive
17.
Korean Journal of Dermatology ; : 68-71, 2011.
Article Dans Coréen | WPRIM | ID: wpr-171982

Résumé

Malignant syphilis (also known as lues maligna) is a rare dermatologic manifestation of syphilis and this is more commonly seen in patients with human immunodeficiency virus (HIV) infection. A 40-year-old man presented with general malaise and widespread cutaneous noduloulcerative lesions covered with lamellar crusts for 15 days. He had been diagnosed with HIV infection 6 years earlier, but had not regularly taken antiretroviral drugs. The syphilis serology showed a VDRL (venereal disease research laboratory) titer of 1 : 256 and a positive TPPA (treponema pallidum particle agglutination test) at presentation. Histologic exam showed the dense perivascular inflammatory infiltrates composed of lymphocytes, histiocysts and neurophils with some plasma cells in the underlying upper and reticular dermis. Obliterated blood vessels with eosinophilic materials were observed as an unusual histologic feature of syphilis. Based on the clinical, histological and serological findings, a diagnosis of malignant syphilis accompanied by acquired immune deficiency syndrome (AIDS) was made. The patient was treated with intramuscular benzathine penicillin G at 2.4 million units per week for 3 weeks, and the skin lesions completely healed with post-inflammatory hyperpigmentation. It is necessary to take into account this entity among the possible diagnoses in HIV-infected patients with cutaneous noduloulcerative lesions.


Sujets)
Adulte , Humains , Syndrome d'immunodéficience acquise , Agglutination , Vaisseaux sanguins , Derme , Granulocytes éosinophiles , Éthylènediamines , VIH (Virus de l'Immunodéficience Humaine) , Infections à VIH , Hyperpigmentation , Lymphocytes , Benzathine benzylpénicilline , Plasmocytes , Peau , Syphilis
18.
Korean Journal of Dermatology ; : 398-407, 2011.
Article Dans Coréen | WPRIM | ID: wpr-34559

Résumé

BACKGROUND: Little is known about the characteristics of tattoos on prisoners. OBJECTIVE: Our purpose was to investigate the clinical characteristics of tattooed prisoners and compare them with other previously reported data. METHODS: Between November 2006 and August 2010, we selected 98 tattooed men in a correctional institution in Seoul and investigated their personal and clinical information, including the average age of their first tattoo, sites of tattoos, contents of tattoos, motivations for getting tattooed, removal of tattoos, and occurrences of medical complications, etc. RESULTS: The most common educational level was the high school graduated group (39.8%). Most tattooed prisoners had a religion (83.7%). Thirty-three of the men (33.7%) had self-injuries. The average age of their first tattoo was 18.5 years, and the average number of tattoos was 2.7. Fifty-three of the tattooed prisoners (54.1%) were first-time offenders. There was a correlation between the number of tattoos and the rate of recidivism. Left arm was the most common site of tattoos (23.6%). Most of the tattoos were performed by others, especially friends (56.1%). Half of the prisoners received their tattoos in society. The most common tattoo material was Chinese ink (41.8%), and the most common motivation for getting tattoos was curiosity (48.0%). Among the various contents of the tattoos, letters were the most frequent (28.1%). Complications were observed in 16 cases (16.3%); hypertrophic scar, keloid, local skin infections, and allergic reactions such as itching. Most of the tattooed prisoners had regrets (80.6%) and requested tattoo removal. Embarrassment was the most common motivation for tattoo removal (35.4%). Removal of tattoos was attempted in 37 cases (37.8%). CONCLUSION: Most of the study results are compatible with those of previous studies. However, education level, religion, and contents of tattoos were slightly different. Further, we obtained new information regarding motivation for tattoo removal, correlation between the number of tattoos and number of crimes, and the attitudes toward their tattoos. We hope the obtained results will be helpful for understanding people with tattoos tattoo in a correctional institution.


Sujets)
Humains , Mâle , Bras , Asiatiques , Carbone , Cicatrice hypertrophique , Crime , Criminels , Comportement d'exploration , Amis , Hypersensibilité , Encre , Chéloïde , Motivation , Prisonniers , Prisons , Prurit , Peau
19.
Annals of Dermatology ; : S119-S122, 2011.
Article Dans Anglais | WPRIM | ID: wpr-224507

Résumé

Familial cutaneous collagenoma is a rare hereditary disease that is inherited in an autosomal dominant pattern. It is characterized by early onset of multiple, skin-colored, sometimes hypopigmented cutaneous nodules, which initially show a symmetrical arrangement on the trunk, and later on the neck and upper limbs. We report on a case of a 45-year-old female who presented with multiple oval to round hypopigmented papules measuring 5~15 mm on her trunk. Histopathologically, the lesions showed an increased amount of collagen fibers and decreased, fragmented elastic fibers in the dermis. The skin lesions were diagnosed as familial cutaneous collagenoma and no treatment was administered. To the best of our knowledge, our case is the first reported case of familial cutaneous collagenoma (FCC) in the Korean literature.


Sujets)
Femelle , Humains , Adulte d'âge moyen , Collagène , Derme , Tissu élastique , Maladies génétiques congénitales , Cou , Peau , Membre supérieur
20.
Korean Journal of Dermatology ; : 567-572, 2010.
Article Dans Coréen | WPRIM | ID: wpr-205779

Résumé

BACKGROUND: Chronic urticaria (CU) is one of the most common skin disorders. This disease commonly induces emotional, social and psychological problems due to the erythematous lesion and intense pruritus. But there has been inadequate objective evaluation of the quality of life (QOL) of the patients with CU in Korea. OBJECTIVE: The purpose of this study was to investigate the QOL of the Korean patients with CU by means of a new disease-specific tool and to assess the association between the QOL and the severity of disease. METHODS: A total of 118 patients with CU were interviewed using the CU QOL questionnaire (CU-Q2oL). Their symptoms were evaluated with the urticaria severity score. We analyzed the relationship between the severity score and the CU-Q2oL score with Pearson's correlation test. RESULTS: The average score of the CU-Q2oL was 50.08+/-18.68. It was high when the patients had high severity scores (p<0.01). The severity score was increased in the patients with old age and when they were married. Comorbid systemic and skin diseases, a long duration of urticaria and systemic symptoms accompanying urticaria were also related to a high severity score. CONCLUSION: This study showed that CU has a significant impact on the QOL of Korean patients with CU in proportion to the disease severity. Clinicians need to consider the QOL and the CU severity of their patients to achieve the ideal goals of treatment.


Sujets)
Humains , Corée , Prurit , Qualité de vie , Peau , Maladies de la peau , Urticaire , Enquêtes et questionnaires
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