Résumé
Twenty rats, divided into 4 equal groups were used. Group I was kept as a control. Group II was exposed to halothane 2% for 20 minutes every other day for 13 exposure. The animals of Group III and IV were subjected for 20 minutes to stress by -hitting on their cages in non-rhythmic fashion. Group III was Exposed to oxygen, while Group IV was exposed to 2% halothane for 13 exposure similar to Group II. Liver sections were stained to detect enzyme activity. Alkaline phosphatase showed moderate increased activity in all groups and it was strong in Von Kupffer cells, cellular infiltrate and bile ducts. Succinic dehydrogenase enzyme was depressed in all groups, however, strong activity was seen in focal hepatocytes in Group IV, Von Kupffer cells and cellular infiltrate. Repeated halothane exposure depressed acid phosphatase activity in Group II but strong activity was seen in the middle and peripheral zones in Group III and IV