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1.
Pediatric Gastroenterology, Hepatology & Nutrition ; : 61-64, 2013.
Article Dans Anglais | WPRIM | ID: wpr-22223

Résumé

Infection-induced acute hepatitis complicated with acute pancreatitis is associated with hepatitis A virus, hepatitis B virus or hepatitis E virus. Although rare, Epstein-Barr virus (EBV) infection should be considered also in the differential diagnosis if the patient has acute hepatitis combined with pancreatitis. We report a case of EBV infection with cholestatic hepatitis and pancreatitis with review of literature. An 11-year-old female was admitted due to 1-day history of abdominal pain and vomiting without any clinical symptoms of infectious mononucleosis. Diagnosis of reactivated EBV infection was made by the positive result of viral capsid antigen (VCA) IgM, VCA IgG, Epstein-Barr nuclear antigen and heterophile antibody test. We performed serologic tests and magnetic resonance cholangiopancreatography to exclude other viral or bacterial infection, autoimmune disorder, and structural problems. The patient's symptoms recovered rapidly and blood chemistry returned to normal with conservative treatment similar to previously reported cases.


Sujets)
Femelle , Humains , Douleur abdominale , Infections bactériennes , Capside , Cholangiopancréatographie par résonance magnétique , Cholestase , Diagnostic différentiel , Infections à virus Epstein-Barr , Hépatite , Virus de l'hépatite A , Virus de l'hépatite B , Virus de l'hépatite E , Herpèsvirus humain de type 4 , Immunoglobuline G , Immunoglobuline M , Mononucléose infectieuse , Pancréatite , Tests sérologiques , Vomissement
2.
Pediatric Gastroenterology, Hepatology & Nutrition ; : 272-275, 2012.
Article Dans Anglais | WPRIM | ID: wpr-85804

Résumé

We report here a case of drug-induced acute pancreatitis proved by elimination and single, low dose challenge test in a child with Crohn disease. A 14-year-old boy with moderate/severe Crohn disease was admitted due to high fever and severe epigastric pain during administration of mesalazine and azathioprine. Blood test and abdominal ultrasonography revealed acute pancreatitis. After discontinuance of the medication and supportive care, the symptoms and laboratory findings improved. A single, low dose challenge test was done to confirm the relationship of the adverse drug reaction and acute pancreatitis, and to discriminate the responsible drug. Azathioprine and 6-mercaptopurine showed positive responses, and mesalazine showed a negative response. We introduce the method of single, low dose challenge test and its interpretation for drug-induced pancreatitis.


Sujets)
Enfant , Humains , Mercaptopurine , Azathioprine , Maladie de Crohn , Effets secondaires indésirables des médicaments , Fièvre , Tests hématologiques , Maladies inflammatoires intestinales , Mésalazine , Pancréatite
3.
Journal of the Korean Radiological Society ; : 157-163, 2004.
Article Dans Coréen | WPRIM | ID: wpr-24608

Résumé

PURPOSE: To identify the brain centers associated with visually evoked sexual arousal in the human brain, and to investigate the neural mechanism for sexual arousal using functional MRI (fMRI). MATERIALS AND METHODS: A total of 20 sexually potent volunteers consisting of 10 males (mean age: 24) and 10 females (mean age: 23) underwent fMRI on a 1.5 T MR scanner (GE Signa Horizon). The fMRI data were obtained from 7 slices (10 mm slice thickness) parallel to the AC-PC (anterior commissure and posterior commissure) line, giving a total of 511 MR images. The sexual stimulation consisted of a 1-minute rest with black screen, followed by a 4-minute stimulation by an erotic video film, and concluded with a 2-minute rest. The brain activation maps and their quantification were analyzed by the statistical parametric mapping (SPM 99) program. RESULTS: The brain activation regions associated with visual sexual arousal in the limbic system are the posterior cingulate gyrus, parahippocampal gyrus, hypothalamus, medial cingulate gyrus, thalamus, amygdala, anterior cingulate gyrus, insula, hippocampus, caudate nucleus, globus pallidus and putamen. Especially, the parahippocampal gyrus, cingulate gyrus, thalamus and hypothalamus were highly activated in comparison with other areas. The overall activities of the limbic lobe, diencephalon, and basal ganglia were 11.8%, 10.5%, and 3.4%, respectively. In the correlation test between brain activity and sexual arousal, the hypothalamus and thalamus showed positive correlation, but the other brain areas showed no correlation. CONCLUSION: The fMRI is useful to quantitatively evaluate the cerebral activation associated with visually evoked, sexual arousal in the human brain. This result may be helpful by providing clinically valuable information on sexual disorder in humans as well as by increasing the understanding of the neuroanatomical correlates of sexual arousal.


Sujets)
Femelle , Humains , Mâle , Amygdale (système limbique) , Éveil , Noyaux gris centraux , Encéphale , Noyau caudé , Diencéphale , Globus pallidus , Gyrus du cingulum , Hippocampe , Hypothalamus , Hypothalamus médial , Système limbique , Imagerie par résonance magnétique , Gyrus parahippocampique , Putamen , Thalamus , Bénévoles
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