Résumé
Hyperpigmentation is one of the cutaneous side effects of chemotherapautic agents, but it is usually accepted as a cosmetic problem. We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin. The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.
Sujets)
Antibiotiques antinéoplasiques/effets indésirables , Bléomycine/effets indésirables , Enfant d'âge préscolaire , Tumeur du sac vitellin/traitement médicamenteux , Femelle , Humains , Hyperpigmentation/induit chimiquement , Facteurs tempsRésumé
We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete recovery.