A Case of Capillary Hemangioma in the External Auditory Canal / 대한이비인후과학회지

Hemangiomas are well known benign tumors that can occur in any sites of the human body. Although it is relatively common to find hemangiomas occurring in the head and neck areas, it rarely occurs in the external auditory canal. We present a case of capillary hemangioma arising from the external auditory canal with extension onto the adjacent outer layer of the tympanic membrane. It was treated with simple excision and myringoplasty. Early recognition may allow for simple excision without myringoplasty.

A Case of Nodular Fasciitis of the Parotid Gland / 대한이비인후과학회지

Nodular fasciitis is a benign proliferation of myofibroblasts and is the most common tumorlike lesion of fibrous tissue. The lesion may easily be misinterpreted as sarcoma, clinically and histologically. The lesion usually presents as a rapidly growing subcutaneous tumor, most commonly located in the extremities and trunks in young adults. The head and neck region, however, is the most common site in infants and children, but rare in adults. We experienced one rare case of intraparotid nodular fasciitis which was treated with superficial parotidectomy. We report this case with a review of literature.

Expression of Cyclooxygenase 1 and 2 in Laryngeal Squamous Cell Carcinoma / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: A large body of evidence from a variety of experimental systems suggests that cyclooxygenase-2 (COX-2) is important in carcinogenesis. This study was to determine whether cyclooxygenase-1 (COX-1) and COX-2 were overexpressed in laryngeal squamous cell carcinoma, and discuss the possible causal role of COX-2 in the laryngeal squamous cell carcinoma formation. MATERIALS AND METHODS: Tissue samples from 21 pateints with laryngeal squamous cell carcinoma were analyzed by immunohistochemical staining. RESULTS: There was an elevation of COX-2 expression in laryngeal squamous cell carcinoma. Normal buccal mucosa biopsies and normal laryngeal epitheliums adjacent to laryngeal cancer showed nondetectable or weak staining for COX-2 protein. There is no difference in the expression of COX -1 in the normal buccal mucosa, normal laryngeal mucosa and laryngeal squamous cell carcinoma. CONCLUSION: There is an overexpression of COX-2, but not COX-1 in laryngeal squamous cell cancer. This may represent a causal role of COX-2 in the formation and proliferation of laryngeal squamous cell carcinoma. There may also be another role of selective COX-2 inhibition for treatment of laryngeal squamous cell carcinoma.