Incidence and severity of COVID-19 infection among health care workers following vaccination: a cross sectional survey in Maharashtra

Background: Despite the vaccines against COVID-19 being proven to be effective, there is the possibility of infection despite vaccination. Such risk may be potentially greater in healthcare workers (HCWs), because of enhanced rates of exposure to the virus at the workplace. The present study was executed to estimate the incidence of COVID-19 infection post vaccination as well as to assess its severity. Methods: A cross-sectional study was initiated in field practice area of one of the tertiary health care institutes in Pune district of Maharashtra. All 700 HCWs were investigated through questionnaire method and detailed data was collected about their vaccination status and related details. Data analysed using Jeffreys's amazing statistics program (JASP), version 0.17.1.0. Results: In the study, 29.23% of the participants showed COVID-19 infection after vaccination. The majority of clinical illnesses were of mild type. Vaccinated participants with pre-existing illnesses had more incidence of COVID-19 infection following vaccination and also the participants with complete doses had a significantly lesser rate of COVID-19 infection post vaccination compared to those with partial doses of the concerned vaccine. Conclusions: Vaccinated individuals pose less risk of severe COVID-19 infections following vaccination than those who are unvaccinated against COVID-19. Pre-existing disease is one of the major risk factors for enhanced incidence and severity of breakthrough infections.

Characterisation of Escherichia coli Recovered from Wild Animals Kept at Bikaner Zoo for Their Antibiotic Resistance

In the present study, a total of 41 E. coliisolates obtained from Boselaphus tragocamelus (5), Antelope cervicapra(18) and Gazella gazelle (18) maintained at Bikaner (Rajasthan) zoo were subjected to antibiogram determination against 15 antibiotics belonging to four different classes and were also genotyped for detecting presence of blaTEM,sul-2, strA and aadAgenes. Antibiogram study revealed highest efficacy of ciprofloxacin (90.2%) followed by nalidixic acid (75.6%) and chloramphenicol (68.4%) and high resistance to β lactam, Sulfamethoxazole and Aminoglycoside antibiotics. The overall presence of blaTEM, sul-2, strA and aadA genes was detected in 95.12%, 80.48%, 60.97% and 87.8% in isolates.

Effect of long-term dehydration on serum constituents in extreme climatic conditions in camel (Camelus dromedarius).

Eight healthy female adult camels were used to study the effect of long term dehydration on serum constituents in extreme climatic conditions viz. cold and hot. The dehydration phases were of 24 days in cold and 13 days in hot conditions. The changes in sodium, potassium, calcium and phosphorus were non significant (P > 0.05) while in chloride, glucose, total proteins, urea, bilirubin, cholesterol and creatinine were significant (P < or = 0.05) during dehydration phase. The mean values of all the constituents tended to return to normal as the rehydration phase advanced. Changes in sodium and potassium in dehydrated camels reflected that they were able to maintain the salt balance.

Spectrum of congenital anomalies associated with biliary atresia.

Several congenital anomalies have been reported in association with biliary atresia. We have analysed the type and frequency of anomalies observed over a 10-year period in consecutive patients operated for extrahepatic biliary atresia at our institution. Of the 107 infants who underwent a laparotomy and surgical correction of biliary atresia, 9 (8.4%) showed significant associated anomalies. Among them, 5 (55.5%) had splenic malformations, 6 (66.6%) had digestive anomalies in the form of malrotation, Meckel's diverticulum and jejunal atresia. One patient had the classical polysplenia syndrome. Our follow-up period was limited (i.e. 5 months) during which time 3 of the 9 (33.3%) patients with associated anomalies became jaundice-free. A higher incidence of malformations found in association with biliary atresia supports the congenital theory and a more thorough search for these anomalies is recommended.

Myelolipoma of adrenal gland in association with occult malignancy--a case report.

Myelolipoma is an unusual lesion of adrenal gland in which ectopic marrow tissue is present. This case is being present because of its rarity.