Recurrent Leiomyosarcoma of The Scrotum.

Leiomyosarcoma of the scrotum is a rare tumor. These tumors usually present as firm, rubbery, nontender, irregular masses. Scrotal leimyosarcomas tend to be slow growing tumors that tend to be present for years. It is best treated by wide local excision. We present a case of recurrent leiomyosarcoma of scrotum in a 57 year old patient, who recurred four times after excision in 3 years and was controlled by combination chemotherapy.

Non-familial paediatric colorectal cancers - an 18 years’ experience.

Background: Primary gastrointestinal malignancies constitute only 1% of all paediatric neoplasms. Aim: The aim of this study was to describe our 18 years’ experience with non-familial paediatric colorectal malignancies, outlining pertinent features of diagnosis, treatment and outcome. Methods: 9 patients of non-familial paediatric colorectal malignancies were admitted in PGIMS, Rohtak, Haryana between 1990 and 2008. After the initial surgical management, the advanced cases underwent chemotherapy and radiation therapy where required and were followed up. Results: There were six male and three female patients (age range: 7 to 16 years). Three tumours arose in the rectum, three in the sigmoid colon, one each in the splenic flexure and appendix, and there was one case of diffuse colonic polyposis. All cases presented with obstruction and rectal bleeding. Two cases of sigmoid carcinoma were unresectable and expired 4 months post-surgery. The rest responded to radical resection. Three patients required palliative radiation therapy. Due to the advanced stage, chemotherapy was given to all the carcinoma patients. One patient had local recurrence after 5 months and another developed distant metastasis. The rest are on follow-up and clinically and radiologically disease free. Conclusion: Paediatric colorectal malignancy is a rare entity, usually diagnosed in the later stages, culminating in advanced disease. A majority of cases undergo radical resection due to the advanced stage of presentation. Advanced stages may also require chemotherapy and radiation therapy.

Advanced sigmoid carcinoma colon.

A 13-year-old female child diagnosed initially as having tuberculosis was subsequently found to have adenocarcinoma colon with secondaries in ovaries and omentum, and proved to be mucinous carcinoma on biopsy. Patient received chemotherapy (FAM) regimen without any relief even 2 months after surgery.