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Indian J Med Sci ; 2010 Sept; 64(9) 391-395
Article Dans Anglais | IMSEAR | ID: sea-145558

Résumé

Background: Safety of blood donor is an important issue for a recipient of blood so all blood donors are to screened for viral such as HBV, HCV, and HIV. Nevertheless, infections sometime occur by blood and its products. Objective: Because we haven't got any awareness about isolated Hbc Ab from a blood donor who presented of occults B hepatitis which can transmit infection to blood recipient, we decided to evaluate HbcAb in a blood donor in this province. Materials and Methods: This is a cross-sectional study on a blood donor in Sistan-Balutuestan province in southeast of Iran in 2010. All individuals referred for blood donation recruited to this. After consent demographic data was recorded from each case, 5 ml blood sample was drawn and centrifuged to separate out the serum and then HbsAb, HbcAb was assayed. Data analyzed by SPSS 16 and frequency, chi- square test, and Fisher exact test was used and if P > 0.05 it was accented as significant association. Result: All individuals were men with age 55 10.5 years. The number of people who had free job was 149 (34.6%) and the number of people whose education level was diploma was 159 (36.9%). About 423 (98.1%) lived in urban areas. The mean weight of men was 76.6 13.7; about 259 (60.1%) men were married. A total of 22 (5.1%) had a positive smoking history. HBc Ab was positive in 87 (20.2%). Nearly all people had HBsAb titer more than 10 IU/L. Conclusion:This study showed that some of the blood donors had isolated HbcAb positive therefore we recommend HbcAb screening for blood donation.


Sujets)
Adulte , Sujet âgé , Donneurs de sang/sang , Anticorps de l'hépatite B/sang , Anticorps de l'hépatite B/isolement et purification , Antigènes de la nucléocapside du virus de l'hépatite virale B/sang , Antigènes de la nucléocapside du virus de l'hépatite virale B/isolement et purification , Antigènes de surface du virus de l'hépatite B/sang , Antigènes de surface du virus de l'hépatite B/isolement et purification , Humains , Iran , Mâle
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