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Braz. j. med. biol. res ; 23(6/7): 547-53, 1990. ilus, tab
Article Dans Anglais | LILACS | ID: lil-92201

Résumé

1. The effect of acute ethanol on memory was studied in an eight-arm radial maze by interposing a 15-s or 1-h delay between the rat's fourth and fifth arma choices. 2. Ethanol (1.0g/Kg) was injected intraperitoneally 5 min prior to the firsrt set of 4-arm choices, therefore being presrnt since the acquisition of the trial-unique event. 3. The results showed 1) a decrease in choice accuracu only in the final 4 arm choices after the 1-h delay, and 2) that errors consisted of re-entries into arms chosen before the delay was imposed. The data further support the contention that ethanol impairs retention of working memory


Sujets)
Rats , Mâle , Animaux , Éthanol/pharmacologie , Apprentissage/effets des médicaments et des substances chimiques , Mémoire/effets des médicaments et des substances chimiques , Comportement spatial , Analyse et exécution des tâches , Rat Wistar , Temps de réaction , /effets des médicaments et des substances chimiques
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