Résumé
Thirty asthmatic children, 5 to 14 years of age, 20 boys and 10 girls, were studied while having acute asthmatic attacks. Each group of 10 children received either a single dose of 6 puffs (1500 micrograms) or 3 doses of 2 puffs (500 micrograms) at 5-minute or 15-minute intervals of terbutaline pressurized aerosol inhaler through a 750-ml volumetric spacer. The onset of bronchodilatation was observed within 2 minutes in all. The 3 doses at 15-minute intervals gave the greatest bronchodilatation throughout the 6-hour study period in comparing with the other two regimens. Slightly insignificant increases in systolic blood pressure and heart rate were observed in all groups and there were no statistically significant differences among them. No serious side effects were observed.
Sujets)
Maladie aigüe , Administration par inhalation , Adolescent , Asthme/traitement médicamenteux , Pression sanguine/effets des médicaments et des substances chimiques , Bronches/effets des médicaments et des substances chimiques , Bronchoconstriction/effets des médicaments et des substances chimiques , Enfant , Enfant d'âge préscolaire , Calendrier d'administration des médicaments , Femelle , Rythme cardiaque/effets des médicaments et des substances chimiques , Humains , Mâle , Répartition aléatoire , Tests de la fonction respiratoire , Terbutaline/administration et posologieRésumé
More than one-third of Thai infants were lactose malabsorbers soon after birth and the percentage of lactose malabsorption increased with age. Beyond 4 years of age, all Thai children studied were lactose malabsorbers. Continued milk supplementation over the study period did not affect the ability to digest lactose in the amount given in the load test. Since the milk-supplemented group of children tended to have better weight gain and few undesirable gastrointestinal symptoms, it seems milk feedings can be used to advantage even among populations with a record of high lactose intolerance.