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The Korean Journal of Thoracic and Cardiovascular Surgery ; : 435-438, 2015.
Article Dans Anglais | WPRIM | ID: wpr-95465

Résumé

Gestational trophoblastic disease (GTD) is a condition of uncertain etiology, choriocarcioma, or placental-site hydatidiform moles, invasive moles, choriocarcinoma, and placental-site trophoblastic tumors. It arises from the abnormal proliferation of trophoblastic tissue and spreads beyond the uterus hematogenously. The early diagnosis of GTD is important to ensure timely and successful management and the preservation of fertility. We report the unusual case of a metastatic choriocarcinoma that formed bullae on the lung surface and presented as recurrent pneumothorax in a 38-year-old woman with elevated beta-human chorionic gonadotropin (hCG) levels. She underwent thoracoscopic wedge resection of the involved lung and four subsequent cycles of consolidation chemotherapy. No other evidence of metastatic disease or recurrent pneumothorax was noted during 22 months of follow-up. GTD should be considered in the differential diagnosis of spontaneous pneumothorax in reproductive-age women with an antecedent pregnancy and abnormal beta-hCG levels.


Sujets)
Adulte , Femelle , Humains , Grossesse , Choriocarcinome , Gonadotrophine chorionique , Chimiothérapie de consolidation , Diagnostic différentiel , Traitement médicamenteux , Diagnostic précoce , Fécondité , Études de suivi , Maladie trophoblastique gestationnelle , Môle invasive , Poumon , Métastase tumorale , Pneumothorax , Tumeur trophoblastique du site d'implantation placentaire , Trophoblastes , Utérus
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