Cheilitis Granulomatosa Treated with Metronidazole / 대한피부과학회지

Cheilitis granulomatosa, a rare disorder of unknown origin, is characterized by recurrent and persistent labial swelling. It is a monosymptomatic form of Melkersson-Rosenthal syndrome. Non-necrotizing granulomatous inflammation is seen at histopathologic examination. We report a 44-year-old woman with a month history of gradual swelling on her upper lip. We treated successfully with oral metronidazole medication for 6 months, although she had showed a poor response in oral prednisolone, antibiotics, several intralesional triamcinolone injection therapy.