A Case of Hypermelanosis in Congenital Adrenal Aplasia / 대한피부과학회지

In adrenal insufficiency, recognition of the disease in its earlier phases may present a real challenge. The disease, if unrecognized and untreated, carries an almost uniformly poor and frequently fatal prognosis. We report a rare case of congenital adrenal aplasia accompanied by hyperpigmentation on the whole body surface. The diagnosis was confirmed by ACTH stimulation test and autopsy findings.

A Mycological and Immunologic Study of Patients with Concurrent Superficial Fungal Infections / 대한피부과학회지

This study was to investigate the relationship between the causative strains and lesional sites and to detect the status of cell mediated immunity in the patients with concurrent fungal infections. The authors performed mycological and immunologic studies on 32 patients with concurrent fungal infections who had visited the dermatologic clinic of Soonchunhyang University HospitaI from July 1982 to June 1983. The results were summarized as follows: It was 18 cases that had the positive cultures in all the lesion sites. Among them 12 cases obtained the same causative strains in all lesions of each patierit. The cultured dermatophytes were Trichophyton rubrum, 10 stains, Trichophyton mentagrophytes, 2 strains. 2. Positive inrnediate hypersitivity reaction was observed only in patients with concurrent fungal infection by trichophytin (87. 5%). 3. For the delayed hypersensitivity reaction, the mean skin reaction scores to PPD, candidin, trichophtin were l. 58, 2. 78, 0. 66 respectively in 32 patients with concurrent fungal infection and 1. 89, 2. 47, l. 50 respectively in 17 controls, but the statistically significancies were only in trichophytin (p<0. 05). 4. The mean percentage of total and active T cell counts in peripheraJ blood were 55. 2%, 23. 9% respectively in 18patients, and 64,0%, 29. 8% in controls(p<0. 05). There was a significant decrease of T-cell count in patients with concurrent fungal infections.