Clinical trial of antidiabetic traditional medicine formulation (TMF) No. 32

Clinical trial to determine the therapeutic efficacy of a traditional antidiabetic drug, TMF-32, was carried out on six Type II NIDDM patients who were admitted to the Traditional Medicine Hospital, Yangon. All patients, 3 males and 3 females, had a fasting blood glucose level of more than 150 mg percent (205.2 + 35.6) and a 2 hour post-prandial blood glucose level of more than 200 mg percent (323.0 + 62.09) and were clinically free from complications of diabetes. The study was a complete cross-over design, using tolbutamide as a control and was conducted under strict diabetic diet wupplying approximately 2500 kcals per day. Hypoglycaemic efficacy calculated from oral glucose tolerance test (OGTT) curves indicated that TMF-32, at doses of 2G and 3G, significantly reduces the blood glucose levels in these patients (p < 0.01 in both doses). The maximum hypoglycaemic effect was seen at approximately 2 hours after dosing and the duration of action lasted only up to 6 hours. Construction of log. dose-response curves showed TMF-32 of having a hypoglycaemic potency of 73 percent of tolbutamide but frequent side effects and cost of drug give rise to contradicting questions on whether it may be useful as a standard traditional antidiabetic drug.

Comparison of two health education methods (Talk & Pamphlet study)

Two health education methods, "talk" and "pamphlet" study, were studied in order to plan health educational activities regarding rheumatic fever in school children in Mandalay Division. The two health education methods, Talk and Pamphlet study, were studied in two groups of school children. Eighty students from V standard and 80 students from IX standard, randomly selected from 4 randomly selected schools: one school from each of the 4 townships of Mandalay City. Each group of 80 students from the V and IX standards were subdivided into two groups using random numbers one group being assigned to the health education talk and the other to the pamphlet study. Pre-test and post-test scores were obtained from the 160 students involved in the study. Analysis of the data using appropriate statistical tests was done. The mean health education level achieved (post-test scores) after health education talk was found to be significantly better than that after the pamphlet study.

An epidemiological study of dental and periodontal disease at the Htaukkyant Sanatorium

An epidemiological survey on deltal and periodoltal disease was comducted at Htaukyant Leprosy Sanatoriul. 165 patients (111 lepromatous and 54 tuberculoid type of leprosy) of age group 25-44 years with history of leprosy not less than 5 years and 40 controls belonging to the same Burmese race were studiedThe results were compared with a similar study done at Phaunggyi village in 1969The overall average number of present and erupted teeth per person, the prevalence of caries and periodontal disease among leprosy patients is not different from people of Phaunggyi. This finding was found to be different from previous reports.