RÉSUMÉ
The suitability of using 2-hydroxy- 1,4-naphthoquinone [Lawsone,I] and some of its synthesized derivatives [II-VI ] as a pigment for printing natural fibers [cotton, wool and silk] was investigated. The effect of varying the structure of 2-hydroxy-1,4-naphthoquinone on the properties of the printed samples was also studied. No change of color and color strength has been observed by introducing -CH2-N [CH2CH2OH] 2 or CH2-N[Et]2 groups in the 3- position of 2-hydroxy- 1,4-naphthoquinone [I] to give derivatives [II] or [III], respectively. On the other hand, the printed samples with semicarbazone derivative [IV] or oxime derivative [V] of 2-hydroxy-1,4-naphthoquinone resulted in an observed change in color and color strength. Furthermore, derivative VI produced by substitution of methylene link in 3-position of a dimeric Lawsone has no affinity for printing cotton, wool and silk
RÉSUMÉ
One hundred and sixty mice were inoculated, either locally in the foot pad or intravenously, with varying concentrations of Mycobacterium leprae. Half these animals were exposed to total body irradiation in order to immunosuppress them. This was in an attempt to establish the pathogenesis of leprosy following the various routes of infection, and the effect of host immunity on the process. Results showed that only limited multiplication occurred following local inoculation of normal mice. The cellular reaction, however, was more extensive in the irradiated animals and acid fast bacilli were observed in larger numbers in the latter group. Concerning remote organs as the liver, spleen and lymph nodes, these were found to be affected only in the intravenously inoculated group and more so in the immunosuppressed animals. These results are discussed