Résumé
Klinefelter syndrome (47, XXY in most cases) is a frequently underdiagnosed chromosomal anomaly associated with multiple comorbidities in adult life. Patients with Klinefelter syndrome have a higher risk of cancer. Specifically, these patients have a higher risk for mediastinal germ cell tumors. It is estimated that 8% of male patients with mediastinal tumors have Klinefelter. We report a 42-years-old male who suffered recurrent respiratory infections. During the study, a mediastinal mass was found, whose pathological study disclosed a type B thymoma. The patient had a history of infertility, high stature, gynecomastia, obesity with gynecoid distribution of body fat and testicular atrophy. A karyotype was requested (47, XXY), confirming the diagnosis of Klinefelter syndrome.
Sujets)
Humains , Mâle , Adulte , Thymome/anatomopathologie , Tumeurs du thymus/anatomopathologie , Syndrome de Klinefelter/anatomopathologie , Thymome/imagerie diagnostique , Tumeurs du thymus/diagnostic , Radiographie thoracique , Tomodensitométrie , Syndrome de Klinefelter/diagnostic , Syndrome de Klinefelter/génétique , Tumeurs du médiastin/diagnostic , Tumeurs du médiastin/anatomopathologieRésumé
A resposta de variáveis pressóricas e de obesidade/adiposidade a um protocolo de exercícios físicos aeróbios, supervisionados, de longa duração foram estudadas durante três anos consecutivos (P1-P3), com sessões de 60 min/dia (30 min. - 60 a 80 porcento FC máx.), 3-5x/semana. Foram incluídos 80 homens adultos (36-74 anos de idade) divididos em grupos de normotensos (GNT) e de hipertensos (GHT). No início (MO) e a cada bimestre (M1-M4) foram verificados o peso, estatura, pregas cutâneas, circunferências e cálculos derivados (IMC, porcento e C/Q). Diariamente, eram registradas a Pressão Arterial Sistólica (PAS), Pressão Arterial Diastólica (PAD) e a Freqüência Cardíaca (FC)...