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Article Dans Anglais | IMSEAR | ID: sea-42595

Résumé

BACKGROUND: Laparoscopic cholecystectomy (LC) has become the treatment of choice for patients with symptomatic cholelithiasis. About 8-15 per cent of patients with symptomatic gallstones may bear associated common bile duct (CBD) stones, The management of choledocholithiasis in the laparoscopic era remain debatable. Although pre-operative endoscopic cholangiopancreatography (ERCP) is available and highly accurate in the detection of CBD stones, its routine use is controversial because of its inherent disadvantages. OBJECTIVE: The aim of this retrospective study was to generate an effective predictive model for bile duct stones detection by pre-operative ERCP. METHOD: Twelve pre-operative clinical, biochemical and sonographic variables from 206 consecutive patients who underwent pre-operative ERCP with LC for gallstones with/without CBD stones from October 1998 to December 2000 were retrospectively analysed RESULTS: 143 of the 206 patients with gallstones were found to have CBD stones. The mean age was 61 (20-93) yr old, and 55.9 per cent were female. Multivariate analysis showed a high predictive value for the presence of CBD stones in patients aged > or = 55 yr old (Odd radio (OR) 1.03, 95% confidence interval (95% CI) 1.01-1.05), jaundice (OR 2.7, 95% CI 1.7-4.8), elevated alkaline phosphatase (OR 1.002, 95% CI 1.000-1.005), CBD dilatation on ultrasound (OR 3.8, 95% CI 1.8-8) and CBD stone on ultrasound. CONCLUSION: The important clinical presentations and investigating could allow more appropriate use of pre-operative ERCP in patients who have symptomatic gallstones with a suspected CBD stone prior to cholecystectomy.


Sujets)
Adulte , Répartition par âge , Sujet âgé , Sujet âgé de 80 ans ou plus , Analyse de variance , Cholangiopancréatographie rétrograde endoscopique/méthodes , Cholécystectomie laparoscopique/méthodes , Lithiase cholédocienne/épidémiologie , Lithiase biliaire/épidémiologie , Études de cohortes , Comorbidité , Femelle , Études de suivi , Humains , Incidence , Modèles logistiques , Mâle , Adulte d'âge moyen , Analyse multifactorielle , Valeur prédictive des tests , Soins préopératoires/méthodes , Probabilité , Études rétrospectives , Appréciation des risques , Indice de gravité de la maladie , Répartition par sexe , Thaïlande/épidémiologie , Résultat thérapeutique
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