Clinical Profile and Outcome of Clinical BCG Disease in Infants.

Objective: To describe the clinical profile, immunological status and outcome of BCG disease in infants. Methods: All infants with a diagnosis of BCG disease in a period of 17 months were followed up. Results: Among 25 infants with BCG disease; 19 had local/ regional involvement and 6 had suspected or confirmed distant/disseminated disease, Mean (range) age of presentation was 3.6 (1.5-9) months. Two of 6 infants with disseminated disease required second-line anti-tubercular treatment. One infant with confirmed disseminated disease had INFγ R1 receptor deficiency. There was no mortality. Conclusion: Most infants with BCG- related disease have local or regional disease.

Severe lipoid pneumonia following aspiration of machine oil: Successful treatment with steroids.

Lipoid pneumonia in children follows mineral oil aspiration and may result in acute respiratory failure. Majority of the patients recover without long-term morbidity, though a few may be left with residual damage to the lungs. We report a case of a two-and-a-half-year-old child with persistent lipoid pneumonia following accidental inhalation of machine oil, who was successfully treated with steroids.

Congenital Nephrotic Syndrome with adrenal calcification and cardiac malformation.

Congenital Nephrotic Syndrome (CNS) with adrenal calcification and CNS with congenital heart disease (CHD) have rarely been reported. However, CNS with both these rare associations has never been previously reported. Here we report a case of CNS with both rare associations, perhaps the first report from India to the best of our knowledge.