Assessment of the sexually abused female children admitted to a tertiary care hospital: Eight year experience

Objective: To discuss the medical, social and legal characteristics of the child sexual abuse and to provide a perspective for gynecologists on this topic

Methods: A retrospective analysis was carried out of the medicolegal records of female children below the age of 18 referred to a tertiary teaching hospital and diagnosed as being exposed to sexual abuse within the family between the years of 2004 to 2012

Results: One hundred and thirty-nine cases were diagnosed as being exposed to sexual abuse during the 8 year period, 23 of them [16.5%] had been involved in sexual abuse within the family. Eleven out of 23 had been admitted as part of a legal process while the rest were reported by a third person

Conclusion: Since sexual abuse within the family is a taboo in Islamic societies, the diagnosis can take a long time. Recognition of sexually abused children, providing early performance of medicolegal examinations, and applying standardized medical guidelines are essential to protect these children

Role of oxidative stress on vaginal bleeding during the first trimester of pregnant women

Reactive oxygen species [ROS] are produced in many metabolic and physiologic processes. Antioxidative mechanisms remove these harmful species. Our aim was to assess whether serum total antioxidant capacity and total oxidant status altered during first trimester pregnancies with vaginal bleeding. In this cross-sectional study, A group of pregnant women at less than 10 weeks of gestation with vaginal bleeding [n=25] and a control group of healthy pregnancies with similar characteristics [n=25] were included. All of the patients in the two groups were matched for age, gestational age and body mass index. Serum total antioxidant capacity and total oxidant status levels were determined using a Hitachi 912 analyzer and compared between the two groups. Characteristics, including maternal age, parity, and gestational age were similar between the two groups. Serum total antioxidant capacity levels were significantly lower in the women with vaginal bleeding than in control women [1.16 +/- 0.20 vs.1.77 +/- 0.08 mmol Trolox Equiv. /L; p=0.001], whereas higher total oxidant status measurements were found in women with vaginal bleeding compared to the control group [4.01 +/- 0.20 vs.2.57 +/- 0.65 micromol H[2]O[2] Equiv. /L; p=0.001]. Increased total oxidant status might be involved in the pathophysiology of vaginal bleeding during early first trimester pregnancies

Skin Findings in Newborns and Their Relationship with Maternal Factors: Observational Research

BACKGROUND: Cutaneous lesions are commonly seen in the newborn period and exhibit inconsistency from the skin lesions of an adult. OBJECTIVE: The present study was carried out with an aim to determine the frequency of physiologic and pathologic cutaneous findings in newborns. METHODS: Typically, 1234 newborns were included in this study. A questionnaire about maternal gestational history, maternal and family history was issued to the parents of each newborn. The presence of cutaneous lesions was recorded. RESULTS: Overall, 642 (52%) of the newborns were male and 592 (48%) were female. Typically, 831 newborns (67.3%) had at least one cutaneous lesion. The prevalence of genital hyperpigmentation and milia was significantly higher in males. In premature newborns, the pervasiveness of cutis marmorata and genital hyperpigmentation was found to be significantly higher. Caput succedaneum, transient neonatal pustular melanosis and cyanosis appeared predominantly in vaginally born infants. Erythema toxicum neonatorum was seen in infants, who were born by cesarean section. The predominance of Mongolian spots and erythema toxicum neonatorum were significantly higher in the newborns of the multiparous mothers; however, caput succedaneum was significantly higher in newborns of the primiparous mothers. CONCLUSION: A number of studies about neonatal dermatoses have been carried out involving different methods in various countries. We consider that our study may be useful in literature, as it has been carried out involving large number of maternal parameters.

Prolonged GnRH suppression period in controlled ovarian hyperstimulation cycles: Impacts on IVF outcomes?

Prolonged GnRH-a administration in IVF cycles may have some advantages related to the treatment outcomes. In this study, we aimed to analyse the effect of prolonged gonadotropin releasing hormone agonist [GnRH-a] administration on controlled ovarian hyperstimulation outcomes of in vitro fertilization [IVF] patients. In this retrospective study, 55 patients with a GnRH-a administration period more than 10 days were compared with 55 patients whose same period was

Analysis of 232 total fertilization failure cycles during intracytoplasmic sperm injection

The intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient. The aim of this study was to identify independent factors which could be used to identify total fertilization failure before the day of intracytoplasmic sperm injection. This was a retrospective study of 232 patients who were admitted to a tertiary-care hospital IVF Unit and showed total fertilization failure during intracytoplasmic sperm injection cycles. To sort out the interwined effects of female age, basal FSH, sperm quality, antral follicle count, starting dose of gonadotrophine, sperm extraction technique, cycle length, >14 mm follicle number, oocyte number after oocyte pick up, estradiol and progesterone level on the day of hCG and the MI, MII and GV oocyte number on the fertilization, multiple logistic regression analysis was used. The total fertilization failure rate was 6% and the recurrance rate was 23%. The original model illustrated that the presence of GV oocytes, total oocyte number less than six, <2000 pg/mL E2 concentration on the day of hCG and testicular sperm extraction increases the total fertilization failure risk. It is very difficult to predict total fertilization failure. Sometimes even with one good quality oocyte and sperm and in the case of globozoospermia fertilization can be achieved. Not only azoospermia but also low oocyte numbers increase the chance of total fertilization failure even after intracytoplasmic sperm injection