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1.
Mongolian Pharmacy and Pharmacology ; : 63-71, 2022.
Article Dans Anglais | WPRIM | ID: wpr-974986

Résumé

Introduction@#In Mongolia, there is opportunity to replace importing products by using raw materials based on the animal and minerals. Those products can be used for medical purposes.</br> In traditional medicine, yellow marrow has been widely used to treat burns and mechanical wounds, as well as frozen and open wounds. The purpose of this study was to determine the pharmacological action of “CIBO” ointment. We created a model of mechanical wound to evaluate the healing of wounds and its index after applying the ointment contains the above mentioned raw materials. @*Material and methods@#Four different groups of “CIBO” ointment was prepared in the technology sector of the Drug Research Institute. Mebo wound ointment was used for comparison as control. The study was con- ducted in the Pharmacology Sector of the Drug Research Institute on white rats of the WISTAR breed under one feeding regime and one condition (12h / 12h). Mechanical wound injury and exposure to open wounds in experimental rats and its size were measured on the 3<sup>rd</sup>, 7<sup>th</sup>, 14<sup>th</sup>, 21<sup>st</sup>, and 28<sup>th</sup> days of treatment. Wound healing, morphology, structure, size, and its index was quan- tified based on the defects. The ointment were applied once a day during the treatment period of 28 days to cover the wound.@*Result@#Mechanical wound showed that study treatment group healed 0-6.2% on the 3<sup>rd</sup> day, 21.4-35.7% on the 7<sup>th</sup> day, 50-60% on the 14<sup>th</sup> day, and 33.3-50% on the 21<sup>st</sup> day separately compared with the untreated group. On the 28<sup>th</sup> day, all the groups were decreased by 66.6%. The wound index was between from 0.002 to 0.0005 in the all experimental groups. Among experimented groups, the group consists of yellow marrow and Chinese white cinder was showed better performance than other groups.@*Conclusion@#The study group 4 (Yellow marrow + Chinese white cinder) has been showed to have a pharmacological action of rapid healing and regeneration of burn wounds caused by experimental rats. It has also been shown to have pharmacological action to regenerate skin tissue and suppress caused by mechanicals. Inclusion of Chinese white cinder in “CIBO” ointment promotes regener ation and healing of “CIBO” ointment.

2.
Mongolian Pharmacy and Pharmacology ; : 32-2013.
Article Dans Anglais | WPRIM | ID: wpr-975984

Résumé

background: Our country’s aging for men of 30-39, 40-49 ages it was accelerated aging process and very accelerated aging process. Aging for men of 50-59, 60- 69 ages it was normal aging and slowed aging process. Aging for women 30-39, 40-49 ages it was normal end slowed aging process. Aging for women 50-59, 60-69 ages it was slowed and significantly slowed aging process. Otherwise, aging for young groups was accelerated and very accelerated aging process, aging for old groups was normal, slowed and significantly slowed aging process. The aging process of men was more quickly than women in our country [1].Aim of the stady: To define biological aging, aging indexes and adaptation potential in population of 18- 25 years old of Ulaanbaatar city.Materials and methods: In total 537 person of 18- 25 years from Ulaanbaatar city were chosen for the research study which was conducted in 2012. Biological age levels were assessed on the basis of following standards. True biological age was determined with clinical-physiologycal indexes and biological age with chronological age. Adaptation potential have been studied with the help of special indexes and analysis were made with the use of regression method. Quantative data of the study has been processed with the use of statistical data processing software SPSS- 19.Results and discussions: Body mass index of 18-25 aged men of Ulaanbaatar city was 22.2146, cachexia 7.82%, normal weight 79.32%, more weight 10.24%, obesity 2.6%, Aging for men of 18-25 ages it was significantly slowed aging process of men was observed 0.37%, slowed aging process 0.55%, normal aging 0.93%, accelerated aging process 12.47%, and very accelerated aging process was 85.66%. The portion of men with normal adaptation potential was 55.67%, adaptation functional tension was 43.76%, unsatisfactory adaptation was 0.55%.Conciusions:1. The portion of cachexia 7.82%, more weight 10.24%, obesity 2.6% of 18-25 aged men of Ulaanbaatar city.2. Health status was abnormal 98.13% of 18-25 aged men of Ulaanbaatar city.3. The portion of 18-25 aged men of Ulaanbaatar city adaptation functional tension 43.76%, unsatisfactory adaptation was 0.55%.References:1. 1 .Tuul M., Lhagva L., Sukhbaatar Ts., AmgalanbaatarD. “Aging biology of Mongolians” III book. “Admon” puplisher. Ulaanbaatar. 2009.2. Open society forum. “Policy of young” abstract. UB. 2010.3. Leonid Kalichman, Ida Malkin, Gregory Livshigts, Oleg Pavlovsky, Valery Bathvich. Variation of Skeletal Biomarkers of biological Aging in a Chuvashian Population: A Longitudinal Stady. American journal of human biology 19:74-81. 2007.4. Apanacenco G.L, Popava L.A, “Medical Valeology”. Kiev. 2000.

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