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Arch. endocrinol. metab. (Online) ; 60(3): 252-263, tab, graf
Article Dans Anglais | LILACS | ID: lil-785225

Résumé

ABSTRACT The proper dietary calcium intake and calcium supplementation, when indicated, are important factors in the acquisition of peak bone mass during youth and in the prevention of fractures in old age. In addition to its deposition in bone, calcium confers an increase in its resistance and exhibits important activities in different enzymatic pathways in the body (e.g., neural, hormonal, muscle-related and blood clotting pathways). Thus, calcium supplementation can directly or indirectly affect important functions in the body, such as the control of blood pressure, plasma glucose, body weight, lipid profile and endothelial function. Since one publication reported increased cardiovascular risk due to calcium supplementation, many researchers have studied whether this risk actually exists; the results are conflicting, and the involved mechanisms are uncertain. However, studies that have evaluated the influence of the consumption of foods rich in calcium have reported no increase in the cardiovascular risk, which suggests that nutritional intake should be prioritized as a method for supplementation and that the use of calcium supplements should be reserved for patients who truly need supplementation and are unable to achieve the recommended daily nutritional intake of calcium.


Sujets)
Humains , Ostéoporose/prévention et contrôle , Os et tissu osseux/effets des médicaments et des substances chimiques , Calcium alimentaire/administration et posologie , Maladies cardiovasculaires/induit chimiquement , Compléments alimentaires/effets indésirables , Agents de maintien de la densité osseuse/administration et posologie , Vitamine D/usage thérapeutique , Calcium alimentaire/effets indésirables , Maladies cardiovasculaires/mortalité , Densité osseuse/effets des médicaments et des substances chimiques , Essais contrôlés randomisés comme sujet , Méta-analyse comme sujet , Calcium/usage thérapeutique , Facteurs de risque , Facteurs âges , Fractures osseuses/prévention et contrôle , Agents de maintien de la densité osseuse/effets indésirables , Apports nutritionnels recommandés
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